Description

Propargyl Bromide

Propargyl Bromide is a high-purity, reactive organic compound used in pharmaceutical, chemical, and research applications as an alkylating agent and building block for synthesis. Known for its high reactivity due to the presence of both a bromide leaving group and an alkyne functional group, it is widely used in the preparation of active pharmaceutical ingredients, fine chemicals, and specialty intermediates. Propargyl Bromide
• Is a reactive organic compound with alkylating and synthetic utility
• Is used as a building block in pharmaceutical and chemical synthesis
• Supports the preparation of specialty chemicals, heterocycles, and drug intermediates
• Is compatible with nucleophilic substitution, coupling, and click chemistry reactions
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Propargyl Bromide is chemically designated as 3-Bromoprop-1-yne. It appears as a colorless to slightly yellow liquid with a pungent odor. It is highly soluble in organic solvents such as dichloromethane, acetone, and ether, and is extremely reactive, requiring careful handling under controlled conditions.
In pharmaceutical and chemical applications, Propargyl Bromide is used in:
• Alkylation reactions for the synthesis of active pharmaceutical ingredients
• Preparation of propargyl-containing heterocycles, carbamates, and ethers
• Click chemistry and bioconjugation for research and drug development
• Intermediate synthesis in fine chemicals, agrochemicals, and specialty polymers
• Laboratory-scale and pilot-scale organic synthesis requiring high-purity halide reagents
Propargyl Bromide’s reactivity allows for selective alkylation and coupling reactions. Due to its toxicity, flammability, and corrosivity, it must be handled with appropriate personal protective equipment, in well-ventilated fume hoods, and stored under inert conditions.
CarboMer supplies Propargyl Bromide with strict control over purity, water content, and residual solvents. The material is suitable for R&D, pilot, and commercial chemical synthesis applications under controlled handling conditions.
The material is packaged in sealed, moisture-resistant, tamper-evident containers with inert gas blanketing. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are provided upon request.
Each batch is tested for identity (NMR, IR), assay, water content, density, and purity. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer specialty reagents and chemical intermediates, Propargyl Bromide is supported by formulation guidance, regulatory compliance advice, and a secure global supply chain to ensure safe, consistent, and reliable use in synthetic applications.