Description

Promazine Hydrochloride USP

Promazine Hydrochloride USP is a pharmaceutical-grade phenothiazine derivative used in the formulation of oral and parenteral medications for the management of agitation, anxiety, and certain psychotic disorders. As a dopamine antagonist with sedative and antipsychotic effects, it serves as a well-established component in neuropsychiatric therapy. Promazine HCl

• Is a USP-compliant active pharmaceutical ingredient (API)
• Is a first-generation antipsychotic with sedative and anxiolytic properties
• Is suitable for tablets, oral solutions, and injectable formulations
• As a water-soluble hydrochloride salt ensures formulation versatility and consistent bioavailability

Chemically classified as a Phenothiazine, Promazine Hydrochloride blocks Dopamine (D2) receptors in the central nervous system, resulting in reduced psychomotor agitation and behavioral disturbances. Its relatively low potency compared to other phenothiazines makes it especially useful where sedation and anxiolysis are therapeutic priorities.

In pharmaceutical formulations, Promazine Hydrochloride USP is used in:

• Oral solid dosage forms (e.g., tablets, capsules) for ambulatory treatment of mild to moderate anxiety and psychomotor agitation
• Oral liquids and solutions for patients with swallowing difficulties or for titratable dosing regimens
• Parenteral formulations (e.g., intramuscular injection) in clinical or hospital settings for acute sedation or preoperative management

Promazine HCl is typically used in short- to medium-duration treatment regimens and is sometimes included as adjunctive therapy in psychiatric protocols. It may also be used off-label for insomnia, nausea, or pre-anesthesia sedation, under appropriate medical supervision.

CarboMer supplies Promazine Hydrochloride USP with strict control over residual solvents, related impurities, and particle size to ensure uniform performance and regulatory compliance. The material conforms to USP monograph specifications and is supported by full regulatory documentation to facilitate global development and registration.

Packaging is available in sealed, light- and moisture-resistant containers. Bulk and small-quantity configurations are available to support research, development, and commercial manufacturing. Minimum order quantities (MOQ), lead times, and CoA documentation are available upon request.

Each batch is tested for identity, assay, pH, related substances, solubility, and microbial limits in compliance with USP guidelines. Full traceability and lot-specific CoAs accompany every shipment.

As with all CarboMer APIs, Promazine Hydrochloride USP is supported by expert regulatory assistance, formulation development guidance, and GMP documentation helping you confidently advance neuropsychiatric drug products to market.