Description

Poly(3-hydroxybutyrate)

Poly(3-hydroxybutyrate) (PHB) is a high-purity, biodegradable biopolymer utilized in pharmaceutical, biomedical, and advanced drug delivery formulations. As a member of the polyhydroxyalkanoate (PHA) family, PHB offers a unique combination of biocompatibility, controlled degradation, and mechanical strength, making it suitable for implantable devices, controlled-release systems, and tissue engineering applications. It

• is a high-purity, pharmaceutical-grade biodegradable polymer
• is fully biocompatible with controlled biodegradation properties
• is suitable for drug delivery systems, implants, and biomedical devices
• Supports sustained-release and tissue-engineering formulations

Poly(3-hydroxybutyrate) is synthesized by microbial fermentation, resulting in a thermoplastic polyester that degrades into non-toxic byproducts such as hydroxybutyric acid. Its degradation profile and mechanical properties can be tailored through molecular weight control and blending, allowing precise customization for various therapeutic applications.

In drug delivery, PHB serves as a matrix former for long-acting injectable formulations, implantable drug reservoirs, and microspheres that enable controlled and sustained drug release. Its slow and predictable degradation allows for extended therapeutic coverage while minimizing repeat dosing and improving patient compliance.

In biomedical applications, PHB is widely studied for surgical sutures, scaffolds for tissue regeneration, and orthopedic implants due to its favorable strength, flexibility, and compatibility with living tissues.

Pharmaceutical developers and procurement teams seeking to purchase Poly(3-hydroxybutyrate) benefit from CarboMer ’s expertise in producing consistent, high-purity materials with full traceability and regulatory alignment. Material is offered in various molecular weight grades, as powders with different particle sizes and as films to support application-specific requirements.

Poly(3-hydroxybutyrate) is delivered in tamper-evident packaging to ensure product integrity during storage and transportation. Minimum order quantities (MOQ), lead times, and comprehensive regulatory support packages are available to facilitate product development and global regulatory submissions.

Every production lot is tested for polymeric properties, molecular weight and other specifications. CarboMer’s validated manufacturing processes ensure batch-to-batch reproducibility, compliance, and performance consistency.

As with all CarboMer excipients and biomaterials, Poly(3-hydroxybutyrate) is supported by formulation guidance, regulatory consulting, and technical assistance throughout the product development lifecycle.