Description

Poloxamer 124 NF

Poloxamer 124 NF is a nonionic triblock copolymer surfactant used in pharmaceutical, cosmetic, and industrial formulations as a solubilizer, emulsifier, dispersing agent, and wetting agent.

• It is compliant with National Formulary (NF) standards
• It is a PEG-PPG-PEG copolymer structure for nonionic emulsification
• It has excellent solubilization of lipophilic compounds in aqueous media
• It is stable across wide pH and temperature ranges
• It is manufactured in cGMP-compliant facilities
• It is supplied with full regulatory documentation

Poloxamer 124 is known for its amphiphilic properties, making it effective in forming micelles for the solubilization of poorly water-soluble drugs. It is used widely in oral liquids, topical creams, ophthalmic solutions, and parenteral formulations.

This excipient improves bioavailability and enhances formulation stability, especially in suspensions and emulsions. It is also compatible with other surfactants, preservatives, and active compounds.

CarboMer supplies Poloxamer 124 NF in bulk with consistent batch reproducibility and tight specification control. It is delivered in sealed, moisture-resistant containers suitable for research, pilot, and commercial production.

Each product batch is tested against NF specifications for identification, assay, and heavy metals. Comprehensive regulatory support includes excipient safety documentation, monograph compliance, and formulation guidance.

As with all CarboMer excipients, Poloxamer 124 NF is supported by technical consulting and quality assurance systems to ensure consistent performance and regulatory readiness in advanced pharmaceutical development.