Description

Novobiocin Sodium Salt USP

Novobiocin Sodium Salt USP is a pharmaceutical-grade Aminocoumarin antibiotic used in research and development of antibacterial and anticancer agents. It functions primarily as an inhibitor of DNA gyrase and has demonstrated potential in modulating molecular chaperones like Hsp90.

• It is a USP-grade antibiotic for research and formulation use
• It inhibits bacterial DNA gyrase and topoisomerase II
• It is explored for anti-MRSA, anti-tuberculosis, and anti-cancer research
• It has high solubility in aqueous systems under neutral to basic pH
• It is manufactured in cGMP-certified facilities
• It is supplied with full regulatory documentation including CoA

Novobiocin Sodium Salt is derived from Streptomyces niveus and is most widely recognized for its ability of inhibiting bacterial DNA supercoiling, making it useful in the treatment of Gram-positive infections. While not widely used clinically today due to resistance profiles, its application in drug discovery and mechanistic biochemistry continues to grow, particularly in oncology and anti-infective development pipelines.

It is commonly used in early-stage pharmaceutical research, high-throughput screening (HTS), and as a control compound in DNA replication studies. Researchers have also explored its utility in modulating heat shock protein (Hsp90), opening avenues for cancer drug development.

CarboMer supplies Novobiocin Sodium Salt USP with guaranteed batch consistency and validated analytical methods. The product is available in sterile and non-sterile grades depending on customer requirements and available for laboratory and pilot-scale use.

All batches are tested to USP standards for identity, potency, and purity, and include microbial testing when applicable. Product documentation includes Certificate of Analysis (CoA).

As with all CarboMer APIs and research products, Novobiocin Sodium Salt USP is backed by our technical support and regulatory expertise—empowering your R&D team to focus on innovation with confidence in material integrity and traceability.