Description

Menadione Sodium Bisulfite USP Trihydrate

Menadione Sodium Bisulfite USP, Trihydrate is a high-purity, water-soluble synthetic form of vitamin K₃ used in pharmaceutical, veterinary, and nutritional formulations to support blood clotting, bone health, and cellular redox function. As a sodium bisulfite derivative of menadione, this compound offers enhanced stability and solubility for aqueous-based preparations. Menadione Sodium Bisulfite

• Is a USP-compliant vitamin K₃ derivative in trihydrate form
• Is used in oral, injectable, and veterinary formulations as a vitamin K supplement
• Supports coagulation pathways and calcium-binding protein synthesis
• Is suitable for human and animal health products requiring water-soluble vitamin K activity
• Is manufactured under Good Manufacturing Practice (GMP) conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and supporting technical data

Menadione Sodium Bisulfite USP, Trihydrate appears as a yellow crystalline powder that is highly soluble in water. It serves as a provitamin that is metabolized in vivo to active vitamin K₂ (Menaquinone), which participates in the γ-carboxylation of glutamic acid residues in clotting factors II, VII, IX, and X.

In pharmaceutical and nutritional applications, Menadione Sodium Bisulfite USP, Trihydrate is used in:

• Oral and parenteral vitamin K therapies for the prevention and correction of hypoprothrombinemia
• Neonatal and pediatric formulations as part of essential vitamin supplementation
• Veterinary products for coagulation support and growth enhancement in livestock
• Adjunct therapies in fat malabsorption disorders and bile duct obstruction
• Premix and feed additive systems in fortified animal nutrition

The Sodium Bisulfite form provides improved chemical stability and compatibility with aqueous vehicles compared to menadione alone, making it ideal for use in injectable, liquid, and feed-grade preparations.

CarboMer supplies Menadione Sodium Bisulfite USP, Trihydrate with validated controls over assay, hydration state, sulfite content, and microbial purity. Each batch complies with United States Pharmacopeia (USP) monograph specifications and is suitable for regulated pharmaceutical and veterinary applications.

The material is packaged in sealed, light-protective, moisture-resistant containers. Available in lab, pilot, and commercial-scale quantities. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are available upon request.

Each batch is tested for identity (UV, IR), assay (anhydrous basis), water content, pH, sulfite determination, heavy metals, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.

As with all CarboMer vitamins and active nutrient ingredients, Menadione Sodium Bisulfite USP, Trihydrate is supported by expert regulatory assistance, formulation guidance, and global sourcing to help you deliver safe and effective health products across human and animal sectors.