Description

(D,L-)-Lactide

(D,L)-Lactide is a high-purity, pharmaceutical- and medical-grade cyclic diester used as a monomer precursor for the production of biodegradable polymers, including poly(D,L-lactide) (PLA) and poly(lactide-co-glycolide) (PLGA). These polymers are widely used in controlled-release drug delivery systems, bioresorbable implants, and medical device applications.

• It is a cyclic diester of lactic acid, composed of equimolar D- and L- enantiomers
• It is used as a monomer for ring-opening polymerization to synthesize PLA and PLGA
• It supports the development of biodegradable microspheres, implants, and coatings
• It is suitable for pharmaceutical, biomedical, and controlled-release formulations
• It is manufactured under Good Manufacturing Practice (GMP) conditions
• It is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and supporting technical data

(D,L)-Lactide is produced by controlled oligomerization and cyclization of racemic lactic acid, yielding a white crystalline solid with high purity and consistent reactivity. The resulting polymers are amorphous due to the racemic composition, enabling predictable degradation rates and drug release kinetics in vivo.

In pharmaceutical and biomedical development, (D,L)-Lactide is used in:

• Ring-opening polymerization to produce poly(D,L-lactide) and PLGA with defined molecular weight and degradation profiles
• Microsphere and nanoparticle fabrication for long-acting injectable formulations of peptides, proteins, and small molecules
• Bioresorbable surgical implants and sutures where predictable resorption is critical
• Coatings and matrices for sustained drug delivery in combination products and medical devices

CarboMer supplies (D,L)-Lactide with tight control over residual monomer content, trace impurities, and moisture levels to ensure reproducible polymerization performance. Each lot is fully traceable and manufactured under GMP conditions to support regulated pharmaceutical and medical device applications.

The material is packaged in sealed, low-moisture, tamper-evident containers to preserve reactivity and prevent premature hydrolysis. Available in research, pilot, and commercial quantities. Minimum order quantities (MOQ), lead times, and full technical documentation are provided upon request.

Each batch is tested for identity, purity, residual lactic acid, melting point, and moisture content in compliance with internal specifications aligned to pharmacopeial and regulatory expectations. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and supporting data accompany every shipment.

As with all CarboMer monomers and excipients, (D,L)-Lactide is supported by technical formulation guidance, regulatory consulting, and supply chain continuity to help you advance safe, effective biodegradable delivery systems to market.