Description

Dalteparin Sodium EP

Dalteparin Sodium EP is a high-purity low molecular weight heparin (LMWH) used in pharmaceutical formulations for the prevention and treatment of thromboembolic disorders. Compliant with European Pharmacopoeia (EP) standards, it is widely used for anticoagulation therapy in surgical, medical, and oncological settings due to its predictable pharmacokinetic profile and reduced risk of bleeding compared to unfractionated heparin.
Dalteparin Sodium is produced by controlled depolymerization of Heparin derived from porcine intestinal mucosa, followed by fractionation to achieve a defined molecular weight distribution. It appears as a white to off-white hygroscopic powder that is freely soluble in water, making it suitable for injectable formulations.
In pharmaceutical and clinical applications, Dalteparin Sodium EP is used in:
• Prophylaxis of deep vein thrombosis following surgery or immobilization
• Treatment of acute venous thromboembolism
• Prevention of clotting during hemodialysis
• Management of cancer-associated thrombosis
• Anticoagulation in acute coronary syndromes
• Clinical research involving coagulation and antithrombotic therapy
Dalteparin Sodium EP exerts its anticoagulant effect primarily by enhancing the inhibition of Factor Xa via antithrombin, with less activity against thrombin (Factor IIa). This selective activity contributes to consistent anticoagulation with fewer monitoring requirements.
CarboMer offers Dalteparin Sodium EP with control over molecular weight distribution, anti-Xa activity, purity, sulfate content, and microbial quality. The material meets EP monograph specifications and is suitable for regulated pharmaceutical manufacturing and clinical use.
The material is packaged in sealed, moisture-protective, tamper-evident containers and handled under controlled conditions. Available in laboratory, pilot, and commercial-scale quantities. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and complete traceability.
Each batch is tested for identity, anti-Xa potency, molecular weight profile, pH, water content, endotoxins, and microbial limits. Technical support is available to assist with formulation, stability considerations, and regulatory compliance.
As with all CarboMer supplied anticoagulant ingredients, Dalteparin Sodium EP is supported by dependable global supply, rigorous quality control, and expert technical guidance to ensure safe, effective, and compliant pharmaceutical product development.