Description

Bupivacaine Hydrochloride USP

Bupivacaine Hydrochloride USP is a high-purity local anesthetic active ingredient used in pharmaceutical formulations for regional, epidural, and spinal anesthesia. Compliant with United States Pharmacopeia (USP) standards, it is widely utilized in injectable dosage forms for surgical procedures, obstetric anesthesia, and pain management.
Bupivacaine Hydrochloride appears as a white to off-white crystalline powder that is freely soluble in water and soluble in alcohol. It is the hydrochloride salt form of Bupivacaine, an amide-type local anesthetic known for its long duration of action and potent nerve-blocking capability.
In pharmaceutical and research applications, Bupivacaine Hydrochloride USP is used in:
• Injectable formulations for regional anesthesia
• Epidural and spinal anesthesia preparations
• Postoperative pain management therapies
• Peripheral nerve block formulations
• Pharmaceutical research involving local anesthetic pharmacology
• Development of controlled-release anesthetic delivery systems
Bupivacaine Hydrochloride USP functions by blocking voltage-gated Sodium Channels in nerve membranes, preventing the initiation and conduction of nerve impulses. This mechanism produces localized loss of sensation without loss of consciousness.
CarboMer supplies Bupivacaine Hydrochloride USP with defined assay, impurity profile, and physicochemical characteristics suitable for regulated pharmaceutical manufacturing and formulation development.
The material meets USP monograph specifications and is appropriate for controlled pharmaceutical production environments.
The material is packaged in sealed, moisture-resistant, tamper-evident containers and protected from excessive light to preserve stability and handling quality. Available in laboratory, pilot, and commercial-scale quantities. Documentation includes Certificate Of Analysis (CoA), Safety Data Sheet (SDS), and full traceability.
Each batch is tested for identity, assay, impurity profile, water content, and related substances where applicable. Technical support is available to assist with formulation development, stability considerations, and regulatory alignment.
As with all CarboMer supplied active pharmaceutical ingredients, Bupivacaine Hydrochloride USP is supported by dependable global supply, rigorous quality systems, and expert technical guidance to ensure consistent and reliable performance across pharmaceutical applications.