Description

Vincristine Sulphate USP

Vincristine Sulphate USP is a high-purity, antineoplastic alkaloid used in pharmaceutical formulations for the treatment of hematologic malignancies and solid tumors. Compliant with United States Pharmacopeia (USP) standards, it functions as a mitotic inhibitor by binding to tubulin, thereby preventing microtubule formation and halting cell division at metaphase. Vincristine Sulphate USP
• Is a USP-compliant antineoplastic alkaloid for injectable pharmaceutical formulations
• Is used in combination chemotherapy regimens for leukemia, lymphoma, and solid tumors
• Acts as a mitotic inhibitor through tubulin binding and microtubule disruption
• Is suitable for sterile injectable dosage forms and oncology research applications
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Vincristine Sulphate is chemically designated as 22-Oxo-vincaleukoblastine sulfate (1:1) (salt). It appears as a white to pale yellow powder, freely soluble in water, and formulated as a sterile solution for intravenous administration.
In pharmaceutical and clinical oncology applications, Vincristine Sulphate USP is used in:
• Injectable formulations for acute lymphoblastic leukemia, Hodgkin’s disease, and non-Hodgkin’s lymphoma
• Combination chemotherapy protocols such as CHOP, MOPP, and VCR-based regimens
• Research and development of new antimitotic cancer therapies
• Veterinary oncology for specific neoplastic diseases in animals
• Compounded preparations requiring precision dosing for patient-specific therapy
Vincristine Sulphate USP demonstrates high potency and selective cytotoxicity toward rapidly dividing cells. Its mechanism of action results in mitotic arrest, apoptosis, and inhibition of tumor growth, making it an essential agent in multi-drug chemotherapy.
CarboMer supplies Vincristine Sulphate USP with control over assay, purity, potency, residual solvents, and microbial limits. Material meets USP monograph specifications and is suitable for regulated pharmaceutical manufacturing.
The material is packaged in sealed, light-protective, tamper-evident containers. It is available in laboratory, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are provided upon request.
Each batch is tested for identity (HPLC, UV), assay (anhydrous basis), potency, pH, residual solvents, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer oncology APIs, Vincristine Sulphate USP is supported by formulation expertise, regulatory compliance, and a secure global supply chain to ensure safe, effective, and high-quality pharmaceutical products.