Description

Valaciclovir HCl

Valaciclovir HCl is a high-purity, antiviral prodrug used in pharmaceutical formulations for the treatment of herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections. It is rapidly converted in vivo to acyclovir, an active antiviral compound that inhibits viral DNA polymerase, preventing viral replication and promoting lesion healing. Valaciclovir HCl is
• A pharmaceutical-grade antiviral for oral dosage forms
• Used in the treatment of herpes simplex and varicella-zoster virus infections
• A prodrug of acyclovir with improved oral bioavailability and dosing convenience
• Suitable for tablets, capsules, and suspension formulations
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Valaciclovir HCl is chemically designated as L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, monohydrochloride. It appears as a white to off-white crystalline powder, freely soluble in water and ethanol, and exhibits excellent chemical stability under standard storage conditions.
In pharmaceutical applications, Valaciclovir HCl is used in:
• Oral tablet and capsule formulations for herpes simplex virus types 1 and 2
• Varicella-zoster virus treatment and postherpetic neuralgia management
• Suppressive and prophylactic antiviral therapy in immunocompromised patients
• Clinical research and development of antiviral combination therapies
• Compounded formulations for customized patient dosing
Valaciclovir HCl provides higher bioavailability compared to acyclovir, enabling less frequent dosing and improved patient adherence. It has a well-characterized safety and efficacy profile across both acute and chronic antiviral therapy.
CarboMer supplies Valaciclovir HCl with control over assay, polymorphic form, residual solvents, and microbial purity. The material is suitable for regulated pharmaceutical manufacturing and development.
The material is packaged in sealed, moisture-resistant, tamper-evident containers. It is available in laboratory, pilot, and commercial-scale quantities. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are provided upon request.
Each batch is tested for identity (IR, HPLC), assay (anhydrous basis), optical purity, water content, residual solvents, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer antiviral APIs, Valaciclovir HCl is supported by formulation guidance, regulatory expertise, and a dependable global supply chain to ensure safe, effective, and compliant pharmaceutical products.