Description

Tramadol Hydrochloride USP

Tramadol Hydrochloride USP is a high-purity, centrally acting analgesic used in pharmaceutical formulations for the management of moderate to moderately severe pain. Compliant with United States Pharmacopeia (USP) standards, it acts through dual mechanisms—μ-opioid receptor agonism and inhibition of serotonin and norepinephrine reuptake—to provide effective and balanced pain relief. Tramadol Hydrochloride USP
• Is a USP-compliant centrally acting analgesic for pharmaceutical use
• Is used in oral, parenteral, and controlled-release formulations
• Provides dual-action analgesia for acute and chronic pain management
• Is suitable for tablets, capsules, injectables, and combination therapies
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Tramadol Hydrochloride is chemically designated as (±)-cis-2-[D(imethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride. It appears as a white or almost white crystalline powder that is freely soluble in water and alcohol, ensuring consistent formulation performance and bioavailability.
In pharmaceutical applications, Tramadol Hydrochloride USP is used in:
• Oral immediate-release and extended-release formulations for pain control
• Injectable solutions for acute pain management in clinical settings
• Combination analgesic products with acetaminophen or NSAIDs
• Compounded formulations for customized dosing or delivery systems
• Clinical research studies evaluating opioid-sparing and multimodal analgesia
Tramadol Hydrochloride USP provides reliable analgesic efficacy with a lower potential for dependence compared to traditional opioids. Its dual mechanism of action offers both central and peripheral modulation of pain signaling pathways.
CarboMer supplies Tramadol Hydrochloride USP with control over assay, purity, polymorphic form, and microbial content. Material meets USP monograph standards and is suitable for regulated pharmaceutical manufacturing.
The material is packaged in sealed, moisture-resistant, tamper-evident containers. It is available in laboratory, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation—including CoA and SDS—are provided upon request.
Each batch is tested for identity (IR, HPLC), assay (anhydrous basis), residual solvents, water content, pH, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer analgesic APIs, Tramadol Hydrochloride USP is supported by formulation expertise, regulatory guidance, and a reliable global supply chain to ensure safe, effective, and compliant pharmaceutical products.