Description

Timolol Maleate USP

Timolol Maleate USP is a high-purity, non-selective beta-adrenergic receptor blocker used in pharmaceutical formulations for the treatment of glaucoma, ocular hypertension, and systemic cardiovascular conditions such as hypertension and angina. Compliant with United States Pharmacopeia (USP) standards, it provides predictable pharmacological performance and stability in ophthalmic and oral dosage forms. Timolol Maleate
• Is a USP-compliant non-selective beta-blocker for pharmaceutical use
• Is used in ophthalmic solutions, tablets, and combination formulations
• Reduces intraocular pressure in glaucoma and ocular hypertension
• Is effective for systemic use in hypertension and cardiac arrhythmia therapy
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Timolol Maleate is chemically designated as (S)-1-(tert-Butylamino)-3-[(4-morpholinyl)-2-hydroxypropoxy]benzene maleate. It appears as a white to off-white crystalline powder, freely soluble in water and suitable for ophthalmic and oral formulations requiring precise dosing and bioavailability.
In pharmaceutical applications, Timolol Maleate USP is used in:
• Ophthalmic solutions and gels for the management of glaucoma and ocular hypertension
• Oral tablets and capsules for hypertension, arrhythmia, and angina management
• Combination therapies with prostaglandin analogs or carbonic anhydrase inhibitors for enhanced ocular efficacy
• Research and clinical studies involving adrenergic receptor modulation
• Compounded formulations requiring reliable solubility and stability
Timolol Maleate USP acts by competitively blocking beta-adrenergic receptors, reducing aqueous humor production in the eye and decreasing heart rate and cardiac workload in systemic applications. Its efficacy and safety are well established in both ophthalmic and cardiovascular therapies.
CarboMer supplies Timolol Maleate USP with control over assay, polymorphic form, residual solvents, and microbial content. Material meets USP monograph specifications and is suitable for regulated pharmaceutical production.
The material is packaged in sealed, moisture-resistant, tamper-evident containers. Available in laboratory, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation, including CoA and SDS, are provided upon request.
Each batch is tested for identity (IR, HPLC), assay (anhydrous basis), water content, residual solvents, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer cardiovascular and ophthalmic APIs, Timolol Maleate USP is supported by formulation expertise, regulatory guidance, and a dependable global supply chain to ensure safe, effective, and compliant pharmaceutical products.