Description

Terbinafine Hydrochloride

Terbinafine Hydrochloride is a high-purity, allylamine antifungal agent used in pharmaceutical formulations for the treatment of fungal infections affecting the skin, nails, and scalp. It acts by inhibiting squalene epoxidase, an essential enzyme in fungal sterol biosynthesis, leading to ergosterol depletion and cell membrane disruption. Terbinafine Hydrochloride
• Is a pharmaceutical-grade allylamine antifungal agent for topical and oral formulations
• Is effective against dermatophytes, molds, and certain yeasts
• Is used in creams, gels, tablets, and nail treatment formulations
• Provides broad-spectrum antifungal activity with rapid onset and long-lasting efficacy
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Terbinafine Hydrochloride is chemically designated as (E)-N-(6,6-Dimethyl-2-hepten-4-yn-1-yl)-N-methyl-1-naphthalenemethanamine hydrochloride. It appears as a white to off-white crystalline powder, sparingly soluble in water but readily soluble in alcohols and polar organic solvents.
In pharmaceutical applications, Terbinafine Hydrochloride is used in:
• Topical creams, gels, and ointments for treatment of tinea infections and dermatomycoses
• Oral tablets for onychomycosis (fungal nail infections) and systemic fungal diseases
• Nail lacquers and medicated coatings for targeted antifungal delivery
• Combination therapies with keratolytic or anti-inflammatory agents
• Research and clinical development of new antifungal dosage forms
Terbinafine Hydrochloride demonstrates potent fungicidal activity with favorable pharmacokinetic properties, allowing shorter treatment durations compared to many other antifungal agents. It is well-tolerated in both topical and systemic use.
CarboMer supplies Terbinafine Hydrochloride with control over assay, particle size, residual solvents, and microbial purity. The material is suitable for regulated pharmaceutical manufacturing and compounding applications.
The material is packaged in sealed, moisture-resistant, tamper-evident containers. Available in laboratory, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation, including CoA and SDS, are provided upon request.
Each batch is tested for identity (IR, HPLC), assay (anhydrous basis), residual solvents, melting point, water content, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer antifungal APIs, Terbinafine Hydrochloride is supported by formulation guidance, regulatory expertise, and dependable global supply to ensure safe, effective, and compliant pharmaceutical products.