Description

(S)-Cyclohexylalanine

(S)-Cyclohexylalanine is a high-purity, enantiomerically pure, non-proteinogenic amino acid used as a building block in the synthesis of peptides, peptidomimetics, and pharmaceutical intermediates. With its hydrophobic Cyclohexyl side chain and defined stereochemistry, (S)-Cyclohexylalanine imparts improved metabolic stability and receptor selectivity in drug development programs.

• It is an enantiomerically pure, (S)-configured non-canonical amino acid
• It is used in peptide synthesis, combinatorial libraries, and medicinal chemistry
• It enhances hydrophobic interactions and conformational rigidity in target compounds
• It is suitable for GMP-compliant active pharmaceutical ingredient (API) intermediates
• It is manufactured under Good Manufacturing Practice (GMP) conditions
• It is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and supporting technical data

Chemically designated as (S)-2-Amino-3-cyclohexylpropanoic acid, this amino acid is incorporated into synthetic peptides to improve binding affinity, bioavailability, and protease resistance. The Cyclohexyl side chain increases hydrophobic surface area, enabling tighter interactions with target proteins or receptors.

In pharmaceutical and biotechnology applications, (S)-Cyclohexylalanine is used in:

• Solid-phase peptide synthesis (SPPS) for therapeutic peptides and analogs
• Peptidomimetic design to improve metabolic stability and oral bioavailability
• Lead optimization programs targeting GPCRs, ion channels, and enzymes
• Research and development of constrained amino acid scaffolds for structural biology and medicinal chemistry

CarboMer supplies (S)-Cyclohexylalanine with validated enantiomeric purity (≥99% ee), consistent particle size, and low residual solvent content. The material is produced under GMP-controlled conditions and fully traceable for regulated applications.

Product is packaged in sealed, moisture-protected, tamper-evident containers. Available in research, pilot, and commercial-scale quantities. Minimum order quantities (MOQ), lead times, and complete technical documentation are provided upon request.

Each batch is tested for identity (NMR, HPLC), chemical purity, enantiomeric excess (chiral HPLC), residual solvents, and microbial content. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and supporting analytical data are included.

As with all CarboMer amino acids and intermediates, (S)-Cyclohexylalanine is supported by technical formulation assistance, regulatory guidance, and dependable supply chain management to help innovators advance high-quality peptide and small-molecule therapies.