Description

Pyridoxine Hydrochloride USP

Pyridoxine Hydrochloride USP is a pharmaceutical-grade form of vitamin B6 used in oral and parenteral formulations to prevent and treat vitamin B6 deficiency, support neurological health, and manage conditions such as nausea during pregnancy and isoniazid-induced neuropathy. With excellent water solubility, stability, and a long-established safety profile, Pyridoxine HCl is widely used in nutritional therapeutics and pharmaceutical preparations. It is

• A USP-compliant vitamin B6 active pharmaceutical ingredient (API)
• Readily water-soluble and highly bioavailable
• Suitable for oral tablets, capsules, solutions, injectables, and prenatal formulations
• Used in the prevention and treatment of vitamin B6 deficiency, nausea/vomiting in pregnancy, and neuropathy

Pyridoxine HCl is the Hydrochloride salt of 3-Hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine, a biologically active form of vitamin B6. It plays a critical role as a coenzyme in amino acid metabolism, neurotransmitter synthesis (e.g., serotonin, dopamine, GABA), and homocysteine regulation.

In pharmaceutical development, Pyridoxine Hydrochloride USP is used in:

• Vitamin supplementation therapies, especially in individuals with poor absorption, increased metabolic need, or drug-induced depletion
• Prenatal formulations to prevent neural tube defects and treat nausea and vomiting during pregnancy (NVP)
• Combination products with Doxylamine succinate for morning sickness relief
• Neuropathy prevention and treatment in patients taking isoniazid or hydralazine
• Nutraceuticals and multivitamin/mineral tablets, often in conjunction with other B vitamins

Its excellent solubility makes it ideal for liquid, injectable, and effervescent formulations, while its chemical stability supports long shelf life under standard storage conditions.

CarboMer supplies Pyridoxine Hydrochloride USP in accordance with strict GMP protocols, offering consistent purity, low impurity levels, and stability. Our product meets or exceeds the specifications outlined in the United States Pharmacopeia (USP) monograph.

The API is packaged in sealed, light- and moisture-protected containers and is available in both standard and bulk pack sizes. Minimum order quantities (MOQ), lead times, and product documentation (CoA, SDS) are available to support formulation development and global submission.

Each batch undergoes rigorous testing for identity, assay, residual solvents, heavy metals, pH, and microbiological quality, ensuring full compliance with pharmacopeial and ICH standards.

As with all CarboMer APIs, Pyridoxine Hydrochloride USP is supported by expert regulatory assistance, formulation guidance, and comprehensive documentation to help pharmaceutical and nutraceutical developers bring high-quality products to market with confidence.