Description

Propylene Glycol USP

Propylene Glycol USP is a high-purity, pharmaceutical-grade solvent and humectant widely used in oral, topical, injectable, and ophthalmic drug formulations. With its excellent solubilizing capacity, low toxicity, and hygroscopic nature, Propylene Glycol supports drug delivery, product stability, and consistent performance across a broad range of dosage forms. Propylene Glycol

• Is a USP-compliant, multifunctional pharmaceutical excipient
• Is a solubilizer and co-solvent for hydrophobic active pharmaceutical ingredients (APIs)
• Is a humectant and stabilizer in oral liquids, injectables, topicals, and ophthalmic formulations
• Is a colorless, odorless, water-miscible liquid with broad formulation compatibility

Chemically known as 1,2-Propanediol, Propylene Glycol is a synthetic diol with high polarity, low vapor pressure, and exceptional solvating power. It enables the incorporation of lipophilic Active Pharmaceutical Ingredients (APIs) into aqueous systems and facilitates uniform drug dispersion, especially in liquid and semisolid formulations.

In pharmaceutical development, Propylene Glycol USP is used in:

• Oral syrups and elixirs to dissolve or disperse poorly soluble APIs
• Injectable formulations as a co-solvent for drugs with low water solubility
• Topical creams, gels, and ointments as a humectant, penetration enhancer, and skin-conditioning agent
• Ophthalmic and nasal solutions to maintain moisture balance and solubilize active compounds
• Soft gelatin capsules as a plasticizer and internal vehicle for hydrophobic drug payloads

Propylene Glycol USP is well-tolerated in therapeutic concentrations and extensively used in both human and veterinary formulations. Its safety profile and regulatory acceptance allow for global product development in diverse dosage forms.

CarboMer supplies Propylene Glycol USP with validated production processes, consistent quality, and low impurity profiles to ensure reproducibility and regulatory compliance.

The material is packaged in tamper-evident, moisture- and light-protected containers, available in various volumes from R&D to bulk commercial scale. Minimum order quantities (MOQ), lead times, and full documentation support are available upon request.

Each batch is tested according to USP monograph specifications for identity, purity, assay, specific gravity, and limits on ethylene glycol and diethylene glycol. Certificates of Analysis (CoA) and Safety Data Sheets (SDS) documents are provided to support your formulation, regulatory, and QA teams.

As with all CarboMer excipients, Propylene Glycol USP is fully supported by expert formulation assistance, regulatory consulting, and lifecycle documentation to accelerate development and bring high-quality pharmaceutical products to market efficiently.