Description

Propantheline Bromide USP

Propantheline Bromide USP is a high-purity, anticholinergic pharmaceutical agent used to reduce gastrointestinal, urinary, and respiratory smooth muscle spasms. Compliant with United States Pharmacopeia (USP) standards, it provides reliable efficacy in the management of hypermotility, peptic ulcers, and conditions associated with excessive secretions. Propantheline Bromide
• Is a USP-compliant anticholinergic agent for smooth muscle relaxation
• Is used in oral tablets and capsules to treat gastrointestinal and urinary disorders
• Reduces hypermotility, cramps, and excessive glandular secretions
• Is suitable for management of peptic ulcers, irritable bowel syndrome, and urinary incontinence
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Propantheline Bromide is chemically designated as 3-(2-Hydroxy-2,2-diphenylacetoxy)-1,1-dimethylpyrrolidinium bromide. It appears as a white crystalline powder that is soluble in water and alcohols, allowing for consistent dosing and formulation flexibility.
In pharmaceutical applications, Propantheline Bromide USP is used in:
• Oral tablets and capsules for the management of gastrointestinal cramps and hypermotility
• Adjunctive therapy in peptic ulcer disease to reduce acid secretion
• Urinary incontinence and hyperactive bladder treatment through smooth muscle relaxation
• Compounded formulations requiring controlled anticholinergic activity
• Research and development of smooth muscle-targeted therapies
Propantheline Bromide USP works by competitively inhibiting muscarinic acetylcholine receptors, leading to relaxation of smooth muscles and decreased glandular secretion. Its pharmacological effects are dose-dependent and predictable, supporting safe and effective clinical use.
CarboMer supplies Propantheline Bromide USP with control over assay, particle size, residual solvents, and microbial content. Each batch meets USP monograph standards and is suitable for regulated pharmaceutical development.
The material is packaged in sealed, moisture-protective, tamper-evident containers. Available in laboratory, pilot, and commercial-scale quantities. Minimum order quantities (MOQ), lead times, and documentation, including Certificates of Analysis (CoA), Safety Data Sheets (SDS), are provided upon request.
Each batch is tested for identity (IR, HPLC), assay, residual solvents, heavy metals, and microbial limits. CoAs and SDS, and full traceability documentation accompany every shipment.
As with all CarboMer anticholinergic APIs, Propantheline Bromide USP is supported by formulation guidance, regulatory expertise, and global supply chain reliability to help develop safe, effective, and compliant pharmaceutical products.