Description

Prilocaine Hydrochloride USP

Prilocaine Hydrochloride USP is a high-purity, amide-type local anesthetic used in pharmaceutical formulations for topical, infiltration, and regional anesthesia. Compliant with United States Pharmacopeia (USP) standards, it provides rapid onset, intermediate duration of action, and low systemic toxicity, making it suitable for dental, dermatological, and minor surgical applications. Prilocaine Hydrochloride
• Is a USP-compliant local anesthetic for pharmaceutical use
• Provides rapid onset and intermediate duration of anesthesia
• Is used in topical creams, gels, infiltration solutions, and regional anesthesia formulations
• Has low systemic toxicity and reduced risk of methemoglobinemia compared with other local anesthetics
• Is manufactured under Good Manufacturing Practice (GMP) conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Prilocaine Hydrochloride is chemically designated as N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride. It appears as a white to off-white crystalline powder, freely soluble in water, alcohol, and other aqueous-compatible solvents, enabling formulation flexibility across oral, topical, and injectable dosage forms.
In pharmaceutical applications, Prilocaine Hydrochloride USP is used in:
• Topical anesthetic creams and gels for minor procedures and skin analgesia
• Infiltration solutions for dental procedures and minor surgeries
• Combined formulations with other local anesthetics, such as lidocaine, for enhanced efficacy
• Regional anesthesia and nerve block formulations
• Compounded formulations requiring precise dosing, sterility, and rapid absorption
Prilocaine Hydrochloride offers a favorable pharmacokinetic profile with rapid tissue penetration and predictable anesthesia onset. Its intermediate duration makes it ideal for procedures requiring both effective pain control and manageable recovery times.
CarboMer supplies Prilocaine Hydrochloride USP with control over assay, particle size, residual solvents, and microbial content. Each batch meets USP monograph specifications and is suitable for regulated pharmaceutical development.
The material is packaged in sealed, moisture-resistant, tamper-evident containers. Available in R&D, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are provided upon request.
Each batch is tested for identity (IR, HPLC), assay (anhydrous basis), residual solvents, pH, heavy metals, and microbial purity. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer local anesthetic APIs, Prilocaine Hydrochloride USP is supported by formulation guidance, regulatory expertise, and global supply chain reliability to help develop safe, effective, and compliant pharmaceutical products.