Description

Poly(vinyl pyrrolidone)

Poly(vinyl pyrrolidone) is a versatile, water-soluble polymer used in pharmaceutical, biopharmaceutical, and personal care applications for its excellent solubilizing, binding, and stabilizing properties. As a non-ionic polymer, it is highly compatible with a wide range of active pharmaceutical ingredients (APIs), excipients, and formulation systems, making it an essential excipient in drug delivery technologies. Poly(vinyl pyrrolidone) is

• A water-soluble, non-ionic polymer with outstanding solubilizing and stabilizing properties
• Used in oral, topical, and injectable formulations for binding, stabilizing, and viscosity modification
• Ideal for controlled-release drug delivery systems, suspensions, and emulsions
• Manufactured under Good Manufacturing Practice (GMP) conditions
• Supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data

Poly(vinyl pyrrolidone) (PVP) is synthesized by the polymerization of N-Vinylpyrrolidone (NVP), and its molecular weight can be controlled to suit specific applications, from low-viscosity solutions to high-strength, gel-like materials. It is highly soluble in water and many organic solvents, forming transparent solutions or gels that can be used as a binder, stabilizer, or solubilizer.

In pharmaceutical and biopharmaceutical applications, Poly(vinyl pyrrolidone) is used in:

• Oral tablets and capsules as a binder and film-former
• Topical formulations including creams, lotions, and gels for skin conditioning and controlled release
• Injectable and ophthalmic formulations to enhance solubility and stabilize drugs in suspension
• Drug delivery systems such as controlled-release tablets and implants
• Lipid-based delivery systems where PVP serves as a stabilizing agent for liposomes and micelles

PVP is widely used in the development of parenteral solutions and suspensions for poorly soluble or unstable drugs. It is also an essential excipient in the formulation of mucosal drug delivery systems (e.g., buccal, nasal, and ocular routes), improving solubility and ensuring stable and effective dosing.

CarboMer supplies Poly(vinyl pyrrolidone) with strict control over molecular weight, viscosity, residual solvents, and microbial contamination. Each batch is produced under GMP-compliant conditions and conforms to pharmacopeial standards for quality and performance.

The material is packaged in sealed, moisture-resistant, tamper-evident containers. Available in R&D, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation, including CoA and SDS, are available upon request.

Each batch is tested for identity (NMR, IR), molecular weight (GPC), viscosity, water content, and microbial purity. All shipments include Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation.

As with all CarboMer excipients and polymers, Poly(vinyl pyrrolidone) is supported by formulation expertise, regulatory guidance, and global supply capabilities to meet the needs of pharmaceutical product developers.