Description

Polysorbate 60 NF

Polysorbate 60 NF is a high-purity, nonionic surfactant and emulsifier used in a wide range of pharmaceutical, nutraceutical, and personal care formulations to enhance solubility, improve dispersion, and stabilize emulsions. Its excellent compatibility with hydrophobic ingredients and regulatory-grade quality make it a trusted excipient in both oral and topical dosage forms. Polysorbate 60 NF

• Is an NF-compliant nonionic surfactant and emulsifier
• Enhances solubility and dispersion of poorly water-soluble active pharmaceutical ingredients (APIs)
• Functions as an emulsifier, wetting agent, and stabilizer in oral, topical, ophthalmic, and mucosal formulations
• Is derived from sorbitol and stearic acid with approximately 20 ethylene oxide units

Polysorbate 60 is chemically defined as Polyoxyethylene (20) sorbitan monostearate, consisting of a sorbitan backbone esterified with stearic acid and ethoxylated to improve hydrophilicity. Its high hydrophilic-lipophilic balance (HLB ~14.9) supports oil-in-water emulsification and dispersion of lipophilic compounds, making it suitable for delivering low-solubility actives across various pharmaceutical systems.

In pharmaceutical formulations, Polysorbate 60, NF is used as:

• A solubilizer for hydrophobic APIs in oral suspensions, emulsions, and softgel systems
• An emulsifier and consistency agent in topical creams, ointments, and lotions
• A stabilizer in protein and biologic formulations to reduce aggregation and surface adsorption
• A wetting and spreading agent in ophthalmic and mucosal delivery platforms

Its low toxicity, nonionic nature, and high tolerability enable its use in sensitive applications, including formulations for pediatric, geriatric, or mucosal routes. It is also widely accepted in cosmetic and dermatological products due to its proven emulsifying performance and skin compatibility.

Pharmaceutical developers and procurement specialists seeking to purchase Polysorbate 60, NF benefit from CarboMer’s GMP manufacturing processes, reliable supply chain, and complete regulatory documentation to support compliant global development.

Material is packaged in sealed, tamper-evident, light- and moisture-protected containers. Standard and bulk sizes are available, and minimum order quantities (MOQ), lead times, and technical support are tailored to your scale and project timeline.

Each lot undergoes full quality control testing for acid value, hydroxyl value, saponification value, peroxide levels, heavy metals, microbial contamination, and compliance with the NF monograph. Certificates of Analysis (CoA) and full traceability documentation are included.

As with all CarboMer excipients, Polysorbate 60, NF is supported by technical formulation guidance, regulatory consultation, and lifecycle development services helping you develop safe, effective, and compliant products from bench to market.