Description

Polyquaternium 2

Polyquaternium 2 is a high-purity, cationic polymer primarily used in pharmaceutical, personal care, and biomedical formulations for its conditioning, film-forming, and antistatic properties. As a quaternary ammonium polymer, it provides strong ionic interaction with negatively charged molecules, enabling stabilization, mucoadhesion, and improved delivery performance across a variety of formulation platforms. Polyquaternium 2

• Is a high-purity cationic polyelectrolyte with quaternary ammonium functionality
• Has excellent film-forming, conditioning, and antistatic properties
• Supports stabilization and bioadhesion in mucosal and topical delivery systems
• Is compatible with oral, topical, ophthalmic, mucosal, and personal care formulations

Polyquaternium 2 consists of vinylimidazolium and acrylamide copolymer units that impart a permanent positive charge to the polymer backbone, providing excellent electrostatic binding capacity with anionic molecules such as mucins, proteins, and nucleic acids. This strong cationic nature allows it to serve as a bioadhesive excipient, enhancing residence time and improving drug absorption across mucosal surfaces.

In pharmaceutical and biomedical applications, Polyquaternium 2 is used as:

• A mucoadhesive polymer in nasal, buccal, ophthalmic, and vaginal delivery systems to enhance drug retention and absorption
• A stabilizer for negatively charged nanoparticle systems and colloidal drug carriers
• A film-forming agent in topical creams, gels, and transdermal formulations, improving spreadability and product aesthetics
• A controlled-release excipient in oral solid dosage forms, prolonging drug release through ionic interaction with anionic APIs

In personal care formulations, Polyquaternium 2 acts as a conditioning agent in shampoos, conditioners, and skin creams, improving hair manageability, providing antistatic benefits, and enhancing skin feel.

Procurement teams and pharmaceutical formulators seeking to purchase Polyquaternium 2 benefit from CarboMer’s validated manufacturing processes, batch reproducibility, consistent molecular weight specifications, and comprehensive regulatory documentation to support global product development and registration.

The material is supplied in sealed, tamper-evident packaging to ensure long-term stability. Minimum order quantities (MOQ), lead times, and full regulatory support documentation are available for early-stage development through commercial-scale production.

Each production batch is subject to validated quality control testing for molecular weight, nitrogen content, residual monomers, heavy metals, and microbial purity to ensure full compliance with pharmaceutical quality standards.

As with all CarboMer excipients and specialty polymers, Polyquaternium 2 is fully supported by formulation consultation, regulatory assistance, and technical services to accelerate your product development and global commercialization strategy.