Description

Poly(caprolactone)

Poly(caprolactone) (PCL) is a pharmaceutical-grade, biodegradable aliphatic polyester used in advanced drug delivery systems, long-acting injectable formulations, implantable devices, and tissue engineering scaffolds. Its slow, predictable biodegradation profile, mechanical strength, and excellent biocompatibility make it a versatile material for sustained-release and biomedical applications. PCL

• Is a pharmaceutical-grade, high-purity biodegradable polyester
• Offers predictable long-term biodegradation into non-toxic metabolites
• Supports controlled-release, implantable, and sustained parenteral delivery systems
• Is fully biocompatible and suitable for drug-eluting implants and tissue scaffolds

Poly(caprolactone) is synthesized via ring-opening polymerization of ε-caprolactone, resulting in a semi-crystalline polymer with a low melting point and flexible thermal processing characteristics. Its long degradation half-life enables extended drug release over weeks to months, making it highly effective for injectable depots, subcutaneous implants, and transdermal reservoirs.

In pharmaceutical formulations, PCL is widely used for microsphere-based sustained-release injectables, drug-eluting implants, and biodegradable wound healing matrices. Its excellent biocompatibility supports use in implantable scaffolds for regenerative medicine, bone regeneration, orthopedic devices, and surgical meshes.

Drug developers and biomedical engineers seeking to purchase Poly(caprolactone) benefit from CarboMer’s precise molecular weight control, validated manufacturing processes, and comprehensive regulatory support to ensure reliable scale-up and global registration.

Each batch undergoes validated analytical testing for molecular weight distribution, crystallinity, residual monomers, heavy metals and microbial limits to ensure full regulatory compliance and reproducibility.

As with all CarboMer biomaterials and excipients, Poly(caprolactone) is supported by end-to-end technical consultation, formulation development support, and regulatory expertise to help accelerate your development programs and ensure smooth global submissions.