Description

Poly(caprolactone) Diol

Poly(caprolactone) diol is a high-purity, biodegradable di-functional polyester used as an excipient, drug delivery carrier, and polymer intermediate for biomedical and pharmaceutical formulations. Its terminal hydroxyl groups enable crosslinking, chemical modification, and the formation of advanced controlled-release, implantable, and regenerative medicine systems. Poly(caprolactone) diol

• Is a high-purity di-functional aliphatic polyester
• has terminal hydroxyl groups that facilitate crosslinking and copolymerization
• Supports long-acting drug delivery systems, implantable devices, and biomedical scaffolds
• Is fully biocompatible and hydrolytically degradable to non-toxic metabolites

Poly(caprolactone) diol is produced through ring-opening polymerization of ε-caprolactone with diol initiators, yielding a linear polymer terminated with two hydroxyl groups. These reactive end groups enable formulation scientists to modify and tailor polymer networks through polyurethane, polycarbonate, or polyether synthesis, expanding its versatility across drug delivery, implantables, and regenerative medicine.

In controlled drug delivery systems, Poly(caprolactone) diol is utilized to create tailored hydrogels, microspheres, and long-acting injectable implants that allow sustained drug release over weeks to months. Its hydrolysis-driven degradation results in gradual breakdown into 6-Hydroxycaproic acid, which is safely metabolized in vivo.

In biomedical engineering, it serves as a key building block for biodegradable scaffolds, orthopedic implants, surgical meshes, and wound healing matrices requiring customized mechanical strength and degradation rates.

Pharmaceutical developers and biomedical manufacturers looking to purchase Poly(caprolactone) diol benefit from CarboMer’s precise molecular weight control, narrow polydispersity, validated manufacturing processes, and complete regulatory support for global product registration.

Each production batch is rigorously tested for molecular weight, hydroxyl value, residual monomers, heavy metals and microbial quality to ensure regulatory compliance and batch-to-batch reproducibility.

As with all CarboMer biomaterials and excipients, Poly(caprolactone) diol is supported by end-to-end technical consultation, formulation development assistance, and regulatory expertise to facilitate rapid progression from R&D to global commercialization.