Description

Poly(acrylic acid) USP, NF

Poly(acrylic acid) USP, NF is a pharmacopeial-grade, high-purity synthetic polymer used extensively as a thickening, stabilizing, suspending, and controlled-release matrix agent in pharmaceutical, biomedical, and personal care formulations. Its anionic carboxyl functionality, high molecular weight, and rheological properties make it an essential excipient for numerous delivery systems requiring viscosity control and bioadhesion.

• USP, NF-grade polyacrylic acid for regulated pharmaceutical applications
• Excellent viscosity control and suspending properties at low concentrations
• Strong mucoadhesive performance for mucosal and ophthalmic delivery systems
• Supports controlled-release and extended-release formulations

Poly(acrylic acid) USP, NF is a high-molecular-weight synthetic polymer formed by polymerization of acrylic acid monomers. Upon hydration, it rapidly swells and forms highly viscous gels, providing robust stabilization for aqueous suspensions, emulsions, creams, and gels. Its ionic character enables stable performance across varying pH ranges, allowing formulation flexibility.

In oral dosage forms, Poly(acrylic acid) USP, NF is widely utilized as a controlled-release matrix former for sustained-release tablets and suspensions. In ophthalmic and mucosal applications, its mucoadhesive properties improve residence time, drug absorption, and patient compliance. In topical and transdermal formulations, it delivers smooth, non-irritating gels that maintain formulation uniformity and stability.

Pharmaceutical formulators, regulatory professionals, and procurement teams seeking to purchase Poly(acrylic acid) USP, NF benefit from CarboMer ’s validated manufacturing processes, batch consistency, and full regulatory documentation to support product development and global registration.

Material is packaged in sealed, moisture-controlled, tamper-evident containers to ensure long-term storage stability. Minimum order quantities (MOQ), lead times, and full technical data packages are available to support both early-stage development and commercial-scale manufacturing.

Each production batch is tested against USP and NF monograph specifications, including identity, viscosity, residual monomers, pH, heavy metals, and microbial limits to ensure consistent performance and full compliance with global regulatory expectations.

As with all CarboMer  excipients, Poly(acrylic acid) USP, NF is supported by expert formulation consulting, regulatory assistance, and technical services to help clients efficiently advance product development from formulation design through regulatory submission and global commercialization.