Description

Poly-D-Aspartic Acid, Sodium Salt USP

Poly-D-Aspartic Acid, Sodium salt USP is a high-purity, water-soluble polypeptide polymer used in pharmaceutical, biomedical, and nutraceutical applications for its chelating, dispersing, and biodegradable properties. As the sodium salt of a synthetic polypeptide composed of L-aspartic acid residues, it provides biocompatibility, controlled release, and functional versatility in drug delivery and tissue engineering formulations. Poly-D-Aspartic Acid, Sodium salt

• Is a USP-compliant water-soluble polypeptide polymer with chelating and dispersing capabilities
• Is used in oral, injectable, and topical dosage forms for stabilization and bioadhesion
• Supports controlled drug release, scaffold formation, and metal ion sequestration
• Is compatible with aqueous, hydrogel, and polymer-blend systems
• Is manufactured under Good Manufacturing Practice (GMP) conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data

Poly-D-Aspartic Acid, Sodium salt USP is synthesized through polymerization of L-aspartic acid monomers followed by neutralization with sodium hydroxide. Its polyanionic structure allows interaction with cationic molecules, enhancing solubility, stability, and bioavailability in formulations.

In pharmaceutical and biomedical applications, Poly-D-Aspartic Acid, Sodium salt USP is used in:

• Controlled-release oral and injectable dosage forms for peptides and small molecules
• Hydrogels and scaffolds in tissue engineering and regenerative medicine
• Chelation of divalent and trivalent metal ions in parenteral and oral formulations
• Ophthalmic and topical preparations for drug stabilization and bioadhesion
• Nutraceuticals and functional foods for moisture retention and controlled delivery of actives

The polymer demonstrates excellent biocompatibility, predictable biodegradation, and low cytotoxicity. Its polyanionic nature contributes to enhanced solubility of hydrophobic actives and improved viscosity control in aqueous systems.

CarboMer supplies Poly-D-Aspartic Acid, Sodium salt USP with validated control over molecular weight, polydispersity, sodium content, and residual monomers. Material is suitable for laboratory, pilot, and commercial-scale production and can be tailored for specific viscosity or chelation needs.

The material is packaged in sealed, moisture-resistant, tamper-evident containers. Minimum order quantities (MOQ), lead times, and documentation, including CoA and SDS, are provided upon request.

Each batch is tested for identity (NMR, IR), molecular weight, sodium content, loss on drying, pH, residual solvents, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.

As with all CarboMer USP-grade polymers and excipients, Poly-D-Aspartic Acid, Sodium salt USP is supported by formulation guidance, regulatory assistance, and a secure global supply chain to ensure safe, effective, and compliant pharmaceutical, biomedical, and nutraceutical product development.