Description

Poly-L-Alanine

Poly-L-Alanine is a high-purity, synthetic polypeptide used in pharmaceutical, biomedical, and tissue engineering applications for its biocompatibility, structural versatility, and biodegradable properties. Composed of repeating L-Alanine residues, it serves as a model polymer for protein-based materials, drug delivery matrices, and scaffolds for regenerative medicine. Poly-L-Alanine

• Is a biocompatible, biodegradable polypeptide polymer
• Is used in drug delivery systems, hydrogels, and tissue engineering scaffolds
• Supports sustained release, cellular adhesion, and mechanical reinforcement
• Is compatible with copolymerization and functionalization for advanced applications
• Is manufactured under Good Manufacturing Practice (GMP) conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data

Poly-L-Alanine is synthesized via polymerization of L-Alanine monomers, producing a linear polypeptide with tunable molecular weight and chain length. Its alpha-helical secondary structure provides mechanical stability and predictable degradation under physiological conditions.

In pharmaceutical and biomedical applications, Poly-L-Alanine is used in:

• Hydrogels and scaffolds for tissue engineering and regenerative medicine
• Controlled-release drug delivery systems, including microspheres and implants
• Biodegradable films, coatings, and biomedical adhesives
• Composite biomaterials blended with other polypeptides or polymers
• Research applications in protein folding, polymer modeling, and biomaterial development

Poly-L-Alanine’s biocompatibility, low immunogenicity, and predictable biodegradation make it suitable for both in vitro and in vivo applications. Its amino acid composition allows for functional modifications, such as conjugation with therapeutic agents or cross-linking with other polymers.

CarboMer supplies Poly-L-Alanine with strict control over molecular weight, polydispersity, moisture content, and residual monomers. The material is provided in powder, lyophilized, or solution forms depending on formulation needs.

The material is packaged in sealed, moisture-protected, tamper-evident containers. Available in research, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation, including CoA and SDS, are provided upon request.

Each batch is tested for identity (NMR, IR), molecular weight distribution, amino acid composition, residual solvents, moisture content, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.

As with all CarboMer specialty polypeptides, Poly-L-Alanine is supported by formulation expertise, regulatory guidance, and reliable global supply to help develop innovative drug delivery, tissue engineering, and biomedical products.