Description

Poloxamer 237 NF

Poloxamer 237 NF is a nonionic surfactant and solubilizer widely used in pharmaceutical formulations for its emulsifying, wetting, and stabilizing properties. Its amphiphilic structure enables compatibility with a broad range of active pharmaceutical ingredients (APIs), enhancing drug solubility, bioavailability, and formulation performance.

• It is an NF-grade, pharmacopeial-compliant nonionic surfactant
• It enhances solubility of poorly soluble compounds
• It functions as emulsifier, wetting agent, and viscosity modifier
• It is compatible with oral, topical, ophthalmic, and parenteral delivery systems
• It is manufactured under Good Manufacturing Practice (GMP) controls
• It is supplied with full regulatory documentation, including CoA

Poloxamer 237 belongs to the class of block copolymers composed of polyethylene oxide (PEO) and polypropylene oxide (PPO) units, offering a unique balance of hydrophilic-lipophilic properties. Its molecular architecture enables effective micelle formation in aqueous systems, making it an excellent choice for solubilizing hydrophobic actives and stabilizing emulsions or dispersions.

In oral formulations, Poloxamer 237 NF can improve dissolution rates and bioavailability for poorly soluble APIs. In parenteral and ophthalmic products, it provides stability, isotonicity adjustment, and reduced irritation potential. Topical and transdermal formulations benefit from its surfactant properties, improving texture, spread ability, and skin feel while maintaining product stability over time.

Pharmaceutical manufacturers and development teams looking to purchase Poloxamer 237 NF will benefit from CarboMer ’s reliable supply chain, tight batch specifications, and robust regulatory support. Material is available in multiple packaging sizes to support development, scale-up, and commercial production.

Poloxamer 237 NF is packaged in moisture-controlled, tamper-evident containers to maintain product integrity. Minimum order quantities (MOQ), lead times, and comprehensive regulatory data packages are available to support efficient procurement and regulatory submission processes.

Every lot is produced using validated manufacturing processes and tested to meet NF specifications for identity, molecular weight distribution, residual solvents, and microbial quality. CarboMer ’s manufacturing excellence ensures consistent product quality, regulatory alignment, and secure global supply.

As with all CarboMer excipients, Poloxamer 237 NF is supported by expert formulation guidance, regulatory consulting, and lifecycle support to help customers accelerate development timelines and meet global regulatory requirements.