Description

Poloxamer 184 NF

Poloxamer 184 NF is a nonionic block copolymer surfactant used in pharmaceutical, dermatological, and cosmetic formulations as a solubilizer, emulsifier, and dispersing agent.

• It meets National Formulary (NF) specifications
• It is a PEG-PPG-PEG triblock copolymer structure for nonionic emulsification
• It solubilizes hydrophobic actives and improves emulsion stability
• It functions effectively in skin care, oral care, and ophthalmic systems
• It is manufactured in cGMP-compliant facilities
• It is supplied with complete documentation including CoA and safety data

Poloxamer 184 is widely used for stabilizing emulsions, suspending poorly soluble actives, and enhancing viscosity profiles. Its biocompatibility and mildness on skin and mucosa make it well suited for topical, ophthalmic, and cosmetic systems. It is frequently included in formulations requiring high clarity and consistent flow characteristics.

The polymer exhibits amphiphilic behavior, forming micelles in aqueous environments that can solubilize lipophilic compounds. It is also used as a co-surfactant in formulations containing anionic or cationic surfactants.

CarboMer provides Poloxamer 184 NF in high-purity, batch-consistent lots suitable for regulated applications. Packaging is optimized for stability and compliance with moisture- and light-sensitive handling requirements.

Every lot is tested according to NF standards for identity, pH, heavy metals, and microbial content. Regulatory documentation includes full compendial compliance, safety data, and formulation compatibility support.

As with all CarboMer excipients, Poloxamer 184 NF is backed by robust technical support, regulatory expertise, and secure supply chain assurance—providing a reliable solution for performance-driven formulation design.