Description

Nicotinamide USP

Nicotinamide USP, also known as niacinamide, is a high-purity, water-soluble form of vitamin B₃ used in pharmaceutical, nutraceutical, and dermatological formulations. As a precursor to coenzymes NAD⁺ and NADP⁺, it plays a vital role in cellular energy metabolism, DNA repair, and anti-inflammatory responses making it a widely used active ingredient across therapeutic and cosmetic markets.

• USP-compliant form of vitamin B₃ with antioxidant and anti-inflammatory activity
• Supports energy metabolism, skin barrier function, and cellular repair
• Used in oral supplements, dermatological topicals, injectables, and fortified foods
• Non-flushing alternative to niacin (nicotinic acid)
• Manufactured under Good Manufacturing Practice (GMP) certified conditions
• Supplied with complete regulatory documentation including Certificate of Analysis (CoA) and supporting technical data

Nicotinamide is a white, odorless, crystalline powder that is highly soluble in water and ethanol. It serves as a biochemical precursor to nicotinamide adenine dinucleotide (NAD⁺), which is essential in redox reactions, ATP production, and sirtuin-mediated gene regulation.

In pharmaceutical and health-related applications, Nicotinamide USP is used in:

• Oral dietary supplements and multivitamins for metabolic and skin health
• Dermatological creams and serums to improve barrier function, reduce redness, and treat acne or hyperpigmentation
• Parenteral and injectable formulations for vitamin deficiency management
• Medical nutrition products targeting niacin-responsive conditions (e.g., pellagra)
• Adjunctive therapies for inflammatory skin diseases, neurodegeneration, and fatigue syndromes

Nicotinamide offers therapeutic benefits without causing the skin flushing often associated with niacin. It is generally well tolerated and can be used in high doses under medical supervision.

CarboMer supplies Nicotinamide USP with validated control over purity, assay, residual solvents, and heavy metals. Each batch meets United States Pharmacopeia (USP) monograph standards and is suitable for use in regulated human drug, dietary supplement, and topical applications.

Material is packaged in sealed, light- and moisture-protective, tamper-evident containers. Available in clinical, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are available upon request.

Each batch is tested for identity (IR, UV), assay, melting range, pH, related substances, loss on drying, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.

As with all CarboMer vitamins and bioactive nutrients, Nicotinamide USP is supported by regulatory expertise, formulation guidance, and a reliable global supply chain to help you bring effective health and skincare products to market.