Mirodenafi USP/EP

Description

Mirodenafil USP/EP is a high-purity phosphodiesterase type 5 (PDE5) inhibitor used in pharmaceutical formulations for the treatment of erectile dysfunction. Compliant with United States Pharmacopeia (USP) and European Pharmacopoeia (EP) standards, it is recognized for its high selectivity for PDE5 and favorable pharmacokinetic profile.

Mirodenafil is chemically designated as 5-(2-Propoxy-5-pyrimidinyl)-2-{(3,4,5-Trimethoxyphenyl)sulfonyl}-1H-pyrrolo[2,3-b]pyridine. It appears as a white to off-white crystalline powder that is sparingly soluble in water and soluble in organic solvents, supporting formulation into oral solid dosage forms.

In pharmaceutical and clinical applications, Mirodenafil USP/EP is used in:

• Oral tablets for management of erectile dysfunction
• Rapid-onset and on-demand erectile dysfunction therapies
• Research involving PDE5 inhibition and nitric oxide signaling
• Pharmacokinetic and bioavailability studies
• Comparative studies among PDE5 inhibitor drug classes

Mirodenafil USP/EP functions by selectively inhibiting PDE5, leading to increased levels of cyclic Guanosine Monophosphate (cGMP) in the corpus cavernosum during sexual stimulation. This results in smooth muscle relaxation and enhanced blood flow, facilitating erectile function. Its selectivity contributes to reduced off-target effects relative to less selective agents.

CarboMer supplies Mirodenafil USP/EP with assay, purity, residual solvents, particle size, and microbial quality. The material meets USP and EP monograph specifications and is suitable for regulated pharmaceutical manufacturing.

The material is packaged in sealed, moisture-resistant, tamper-evident containers and protected from excessive light. Available in laboratory, pilot, and commercial-scale quantities where permitted. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and full traceability.

Each batch is tested for identity (IR, HPLC), assay on anhydrous basis, impurity profile, water content, and microbial limits. Technical support is available to assist with formulation considerations and regulatory compliance.

As with all CarboMer supplied active pharmaceutical ingredients, Mirodenafil USP/EP is supported by dependable global supply, stringent quality control, and expert technical guidance to ensure safe, effective, and consistent pharmaceutical product development.