Description

Hydroxypropyl Cellulose USP

Hydroxypropyl Cellulose USP is a versatile cellulose ether used in pharmaceutical formulations as a binder, film-former, and matrix-forming agent, especially valued for its thermoplasticity, low toxicity, and bioadhesive properties.

• USP-grade cellulose derivative with multifunctional excipient performance
• Soluble in water and ethanol; forms clear, flexible films
• Acts as binder, matrix-former, and mucoadhesive in oral dosage forms
• Compatible with hot-melt extrusion and spray-drying technologies
• Manufactured under ISO 9001:2015 and cGMP-compliant systems
• Supplied with complete regulatory support including CoA, DMF, and compendial data

Hydroxypropyl Cellulose (HPC) is a partially substituted cellulose polymer that dissolves in aqueous and organic solvents. It forms thermoplastic, compressible films and is often used in sustained-release formulations, especially in granulation and film-coating applications.

Its thermal gelling and rheological properties make it a preferred choice for matrix-controlled oral tablets, ophthalmic vehicles, and buccal patches. HPC also serves as a carrier in solid dispersions and melt-based delivery systems.

Carbomer supplies Hydroxypropyl Cellulose USP in multiple particle sizes and viscosity grades tailored to specific formulation needs. Material is packaged in sealed, moisture-controlled containers for optimal handling and shelf stability.

Each batch is tested to USP specifications for identity, viscosity, loss on drying, residue on ignition, and microbial profile. Documentation includes full regulatory files, analytical methods, and compatibility guidelines.

As with all Carbomer excipients, Hydroxypropyl Cellulose USP is supported by dedicated formulation and compliance teams to ensure success in development, scale-up, and global registration strategies.