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Hydroquinone USP

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Description

Hydroquinone USP

Hydroquinone USP is a high-purity, pharmaceutical-grade skin-lightening agent used in topical formulations to treat hyperpigmentation disorders, including melasma, lentigines, and post-inflammatory discoloration. As a potent melanin synthesis inhibitor, Hydroquinone is a key active in dermatological creams and gels for regulated depigmentation therapy. Hydroquinone

  • Is a USP-compliant phenolic compound with proven efficacy in skin depigmentation
  • Inhibits Ttyrosinase, the rate-limiting enzyme in melanin production
  • Suitable for prescription and over-the-counter (OTC) topical preparations
  • Is used in creams, gels, serums, and compounding bases for hyperpigmentation
  • Is manufactured under Good Manufacturing Practice (GMP) conditions
  • Supplied with complete regulatory documentation including Certificate of Analysis (CoA) and supporting technical data

Chemically known as 1,4-Benzenediol, Hydroquinone appears as a white crystalline powder that is sparingly soluble in water and freely soluble in alcohol. It acts by interfering with melanin synthesis in melanocytes, resulting in gradual lightening of hyperpigmented areas when applied consistently.

In pharmaceutical and cosmetic dermatology, Hydroquinone USP is used in:

  • Prescription-strength topical depigmenting agents (2–4% formulations)
  • OTC skin-lightening creams and spot correctors for dark spots and age spots
  • Combination therapies with retinoids or corticosteroids to enhance efficacy and reduce irritation
  • Compounded dermatological treatments for melasma, chloasma, and freckles
  • Post-acne or post-inflammatory hyperpigmentation regimens

Hydroquinone is often used in regulated concentrations due to its potency and should be formulated with proper pH control and antioxidants to maintain stability and reduce oxidation during storage.

CarboMer supplies Hydroquinone USP with stringent control over assay and impurities. Each batch conforms to United States Pharmacopeia (USP) specifications and is suitable for regulated topical product development.

The material is packaged in light-protective, tamper-evident containers under nitrogen where necessary. Available in laboratory, pilot, and commercial volumes. Minimum order quantities (MOQ), lead times, and complete documentation—including CoA and SDS—are available upon request.

Each batch is tested for identity (IR, UV), assay, melting range, related substances, residue on ignition, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation are included.

As with all CarboMer dermatological actives and APIs, Hydroquinone USP is supported by regulatory guidance, formulation assistance, and reliable global sourcing to help you bring safe, effective, and compliant skin care therapies to market.

Additional information

Dimensions 1 × 1 × 1 cm