Description

Gentamicin Sulfate

Gentamicin Sulfate is a high-purity aminoglycoside antibiotic used in pharmaceutical formulations for the treatment of serious infections caused by susceptible gram-negative and certain gram-positive bacteria. It is commonly utilized in injectable, topical, ophthalmic, and otic dosage forms due to its broad-spectrum antibacterial activity.
Gentamicin Sulfate is a mixture of related aminoglycoside components produced by fermentation of Micromonospora species and subsequently converted to the sulfate salt. It appears as a white to off-white hygroscopic powder that is freely soluble in water, making it suitable for aqueous formulations.
In pharmaceutical and clinical applications, Gentamicin Sulfate is used in:
• Injectable formulations for severe systemic bacterial infections
• Topical creams and ointments for skin and soft tissue infections
• Ophthalmic and otic solutions for eye and ear infections
• Treatment of infections caused by Pseudomonas, Escherichia coli, Klebsiella, and related organisms
• Combination antimicrobial therapies
• Research involving bacterial protein synthesis inhibition
Gentamicin Sulfate functions by binding to the 30S ribosomal subunit of bacteria, disrupting protein synthesis and leading to bacterial cell death. Its bactericidal activity and concentration-dependent killing make it effective in acute care settings.
CarboMer supplies Gentamicin Sulfate with details of potency, component profile, purity, residual solvents, and microbial quality. The material is suitable for regulated pharmaceutical manufacturing and clinical use.
The material is packaged in sealed, moisture-resistant, tamper-evident containers. Available in laboratory, pilot, and commercial-scale quantities. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and complete traceability.
Each batch is tested for identity, assay, component composition, pH, water content, and microbial limits. Technical support is available to assist with formulation development and regulatory compliance.
As with all CarboMer supplied antibiotic active ingredients, Gentamicin Sulfate is supported by dependable global supply, stringent quality control, and expert technical guidance to ensure safe, effective, and consistent pharmaceutical product development.