Description

Furosemide

Furosemide is a high-purity loop diuretic used in pharmaceutical formulations for the management of edema and hypertension associated with congestive heart failure, renal disease, hepatic cirrhosis, and other conditions involving fluid overload. It is one of the most widely prescribed diuretics due to its rapid onset and strong natriuretic effect.
Furosemide is chemically designated as 4-Chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid. It appears as a white to off-white crystalline powder that is practically insoluble in water and soluble in alkaline solutions and certain organic solvents, allowing formulation into oral and injectable dosage forms.
In pharmaceutical applications, Furosemide is used in:
• Oral tablets and capsules for treatment of edema and hypertension
• Injectable formulations for acute fluid overload and emergency care
• Management of pulmonary edema and congestive heart failure
• Treatment of edema associated with renal and hepatic disorders
• Research involving renal physiology and electrolyte balance
• Combination antihypertensive and diuretic therapies
Furosemide functions by inhibiting the sodium-potassium-chloride cotransporter in the thick ascending limb of the loop of Henle, leading to increased excretion of sodium, chloride, and water. This mechanism results in rapid diuresis and reduction of extracellular fluid volume.
CarboMer supplies Furosemide with details of assay, purity, residual solvents, particle size, and microbial quality. The material is suitable for regulated pharmaceutical development and commercial manufacturing.
The material is packaged in sealed, moisture-resistant, tamper-evident containers. Available in laboratory, pilot, and commercial-scale quantities. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and full traceability.
Each batch is tested for identity (IR, HPLC), assay on anhydrous basis, impurity profile, water content, and microbial limits. Technical support is available to assist with formulation considerations and regulatory compliance.
As with all CarboMer supplied cardiovascular and renal active ingredients, Furosemide is supported by dependable global supply, stringent quality control, and expert technical guidance to ensure safe, effective, and consistent pharmaceutical product development.