Description

Fondaparinux Sodium

Fondaparinux Sodium is a high-purity synthetic pentasaccharide anticoagulant used in pharmaceutical formulations for the prevention and treatment of thromboembolic disorders. It is structurally related to the antithrombin-binding sequence of Heparin but is produced entirely by chemical synthesis, providing high specificity and batch-to-batch consistency.
Fondaparinux Sodium is chemically designated as the sodium salt of a synthetic sulfated pentasaccharide. It appears as a white to off-white hygroscopic powder that is freely soluble in water, making it suitable for formulation into injectable aqueous solutions.
In pharmaceutical and clinical applications, Fondaparinux Sodium is used in:
• Prophylaxis of deep vein thrombosis following orthopedic or abdominal surgery
• Treatment of acute deep vein thrombosis and pulmonary embolism
• Management of acute coronary syndromes
• Anticoagulation therapy requiring predictable pharmacokinetics
• Clinical research involving selective Factor Xa inhibition
Fondaparinux Sodium exerts its anticoagulant effect by selectively binding to antithrombin and enhancing inhibition of Factor Xa, without direct activity against thrombin (Factor IIa). This highly specific mechanism results in predictable anticoagulation with a reduced risk of heparin-induced thrombocytopenia.
CarboMer supplies Fondaparinux Sodium with details of molecular integrity, sulfate content, purity, residual solvents, and microbial quality. The material is suitable for regulated pharmaceutical development and clinical manufacturing.
The material is packaged in sealed, moisture-protective, tamper-evident containers and handled under controlled conditions. Available in laboratory, pilot, and commercial-scale quantities where permitted. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and complete traceability.
Each batch is tested for identity, assay, sulfate content, water content, endotoxins, and microbial limits. Technical support is available to assist with formulation considerations, stability, and regulatory compliance.
As with all CarboMer supplied anticoagulant ingredients, Fondaparinux Sodium is supported by dependable global supply, stringent quality control, and expert technical guidance to ensure safe, effective, and consistent pharmaceutical product development.