Description

Fentanyl Citrate EP/USP

Fentanyl Citrate EP/USP is a high-purity synthetic opioid analgesic used in pharmaceutical formulations for the management of severe pain and as an anesthetic adjunct in surgical and critical care settings. Compliant with both European Pharmacopoeia (EP) and United States Pharmacopeia (USP) standards, it is recognized for its rapid onset, high potency, and short duration of action when administered under controlled medical supervision.
Fentanyl Citrate is chemically designated as N-Phenyl-N-(1-(2-phenylethyl)piperidin-4-yl)propanamide citrate. It appears as a white to off-white crystalline powder that is freely soluble in water, allowing formulation into injectable solutions, transdermal systems, and other specialized dosage forms.
In pharmaceutical and clinical applications, Fentanyl Citrate EP/USP is used in:
• Injectable formulations for anesthesia and perioperative pain control
• Analgesic therapy for severe acute and chronic pain
• Adjunctive use in general and regional anesthesia
• Management of pain in oncology and palliative care settings
• Research involving opioid receptor pharmacology and analgesic mechanisms
Fentanyl Citrate EP/USP exerts its pharmacological effect by selectively binding to μ-opioid receptors in the central nervous system, resulting in potent analgesia and sedation. Its high lipid solubility allows rapid penetration of the blood–brain barrier, contributing to its fast onset of action.
CarboMer supplies Fentanyl Citrate EP/USP with details of assay, purity, residual solvents, particle size, and microbial quality. The material meets EP and USP monograph specifications and is suitable for regulated pharmaceutical manufacturing and clinical use under strict control.
The material is packaged in sealed, tamper-evident, and controlled-access containers in accordance with applicable handling requirements. Available in laboratory, pilot, and commercial-scale quantities where permitted. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and complete traceability.
Each batch is tested for identity (IR, HPLC), assay on anhydrous basis, citrate content, impurity profile, water content, and microbial limits. Technical support is available to assist with formulation considerations, compliance, and controlled handling procedures.
As with all CarboMer supplied controlled pharmaceutical ingredients, Fentanyl Citrate EP/USP is supported by dependable global supply, rigorous quality control, and expert technical guidance to ensure safe, compliant, and consistent pharmaceutical product development.