Description

Etofenamate

Etofenamate is a high-purity, nonsteroidal anti-inflammatory drug (NSAID) used topically to relieve pain, swelling, and inflammation associated with musculoskeletal disorders, including arthritis, sprains, and tendonitis. As a flufenamic acid derivative, Etofenamate is specifically formulated for transdermal absorption, offering localized therapeutic action with reduced systemic exposure. Etofenamate

• Is a topical NSAID for treatment of joint and muscle pain, inflammation, and soft tissue injuries
• Is a derivative of Flufenamic acid with enhanced skin permeability
• Is suitable for gels, creams, sprays, and medicated patches
• Acts as an anti-inflammatory, analgesic, and antirheumatic agent
• Is manufactured under Good Manufacturing Practice (GMP) conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and supporting technical data

Chemically designated as 2-hydroxyethyl 2-[(3-ethoxyphenyl)amino]benzoate, Etofenamate is a lipophilic ester designed to penetrate skin and reach inflamed tissues beneath the dermis. It inhibits cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins that mediate pain and inflammation.

In pharmaceutical applications, Etofenamate is used in:

• Topical gels and creams for localized treatment of joint and muscle conditions
• Transdermal patches and sprays for extended release and patient convenience
• Sports medicine formulations targeting acute injuries and inflammation
• Combination products with muscle relaxants or cooling agents for enhanced effect

Etofenamate is especially favored for its high local bioavailability and minimal systemic absorption, making it ideal for chronic conditions requiring sustained pain and inflammation management with a lower risk of gastrointestinal or cardiovascular side effects typical of oral NSAIDs.

CarboMer supplies Etofenamate with tight control over assay, residual solvents, impurities, and particle size distribution to support topical pharmaceutical manufacturing. Each batch is produced under GMP conditions and meets global regulatory requirements.

The material is packaged in sealed, light- and moisture-protective, tamper-evident containers. Available in pilot and commercial-scale quantities. Minimum order quantities (MOQ), lead times, and technical documentation (including CoA and SDS) are available upon request.

Each batch is tested for identity (IR, HPLC), assay, related substances, residual solvents, and microbial purity. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.

As with all CarboMer topical actives and NSAIDs, Etofenamate is supported by formulation expertise, regulatory assistance, and secure supply chain management to help you deliver safe, effective, and patient-friendly topical therapies.