Description

Dexamethasone Sodium Phosphate USP

Dexamethasone Sodium Phosphate USP is a high-purity, water-soluble corticosteroid used in pharmaceutical formulations for the treatment of inflammatory, allergic, autoimmune, and immunosuppressive conditions. Compliant with United States Pharmacopeia (USP) standards, it is the phosphate ester prodrug of Dexamethasone, designed to provide rapid onset of action and suitability for injectable and ophthalmic dosage forms.
Dexamethasone Sodium Phosphate is chemically designated as Sodium 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-phosphate. It appears as a white to slightly yellow, hygroscopic crystalline powder that is freely soluble in water, enabling formulation into sterile aqueous solutions.
In pharmaceutical and clinical applications, Dexamethasone Sodium Phosphate USP is used in:
• Injectable formulations for acute inflammatory and allergic reactions
• Ophthalmic solutions for ocular inflammation and postoperative care
• Management of cerebral edema and spinal cord compression
• Adjunct therapy in oncology and palliative care settings
• Treatment of severe asthma, anaphylaxis, and autoimmune disorders
• Research involving glucocorticoid receptor modulation
Dexamethasone Sodium Phosphate USP exerts potent anti-inflammatory and immunosuppressive effects by modulating gene expression and inhibiting the release of inflammatory mediators such as prostaglandins and cytokines. Its phosphate ester improves aqueous solubility, allowing rapid systemic availability following parenteral administration.
CarboMer supplies Dexamethasone Sodium Phosphate USP with control over assay, purity, residual solvents, particle size, and microbial quality. The material meets USP monograph specifications and is suitable for regulated pharmaceutical manufacturing and clinical use.
The material is packaged in sealed, moisture-protective, tamper-evident containers. Available in laboratory, pilot, and commercial-scale quantities. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and complete traceability.
Each batch is tested for identity (IR, HPLC), assay on anhydrous basis, pH, water content, impurity profile, and microbial limits. Technical support is available to assist with formulation considerations and regulatory compliance.
As with all CarboMer supplied corticosteroid ingredients, Dexamethasone Sodium Phosphate USP is backed by rigorous quality control, and expert technical guidance to ensure safe, effective, and consistent pharmaceutical product development.