Description

D-γ-Tocotrienol

D-γ-Tocotrienol is a high-purity member of the Vitamin E family used in pharmaceutical, nutraceutical, and biomedical research applications for its potent antioxidant, anti-inflammatory, and lipid-modulating properties. As a naturally occurring tocotrienol isomer, it differs structurally from tocopherols by possessing an unsaturated isoprenoid side chain, which contributes to enhanced cellular uptake and biological activity.
D-γ-Tocotrienol is chemically designated as (2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltrideca-3,7,11-trienyl]-6-chromanol. It appears as a pale yellow to amber oily liquid that is insoluble in water but soluble in lipids and organic solvents. Due to its sensitivity to light, heat, and oxygen, it is typically handled under controlled conditions.
In pharmaceutical, nutritional, and research applications, D-γ-Tocotrienol is used in:
• Antioxidant formulations targeting oxidative stress and inflammation
• Nutraceutical supplements for cardiovascular and metabolic support
• Research involving cholesterol biosynthesis and HMG-CoA reductase modulation
• Studies of neuroprotection and cellular signaling pathways
• Lipid-based drug delivery systems and emulsions
• Functional food and cosmetic research applications
D-γ-Tocotrienol exhibits strong free-radical scavenging activity and has been shown in research settings to modulate inflammatory pathways and lipid metabolism more effectively than some tocopherol forms. Its unsaturated side chain allows better penetration into lipid membranes, enhancing antioxidant performance at the cellular level.
CarboMer supplies D-γ-Tocotrienol with control over isomeric purity, assay, oxidation markers, residual solvents, and microbial quality. The material is suitable for regulated research, nutraceutical development, and advanced formulation applications.
The material is packaged in sealed, light-resistant, oxygen-protective, tamper-evident containers. Available in laboratory and pilot-scale quantities. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and complete traceability.
Each batch is tested for identity (HPLC, NMR), assay, isomeric composition and peroxide value. Technical support is available to assist with formulation design, stabilization strategies, and application development.
As with all CarboMer supplied Vitamin E derivatives, D-γ-Tocotrienol is supported by dependable global supply, stringent quality control, and expert technical guidance to ensure consistent and reliable performance in pharmaceutical, nutritional, and research applications.