Description

Cimetidine USP

Cimetidine USP is a high-purity histamine H2-receptor antagonist used in pharmaceutical formulations for the treatment of gastrointestinal conditions associated with excess gastric acid secretion. Compliant with United States Pharmacopeia (USP) standards, it is widely utilized in oral and injectable dosage forms.
Cimetidine is chemically designated as N-Cyano-N’-methyl-N”-[2-[(5-methyl-1H-imidazol-4-Yl)methylthio]ethyl]guanidine. It appears as a white to off-white crystalline powder that is soluble in water and suitable for formulation into tablets, solutions, and injectable preparations.
In pharmaceutical and research applications, Cimetidine USP is used in:
• Oral tablet and liquid formulations for acid-related disorders
• Treatment of peptic ulcers and gastroesophageal reflux disease
• Management of hypersecretory conditions such as Zollinger–Ellison syndrome
• Injectable formulations for hospital and acute care use
• Research involving histamine receptor pharmacology
• Studies of gastric acid secretion and gastrointestinal physiology
Cimetidine USP functions by selectively blocking Histamine H2-Receptors on gastric parietal cells, reducing gastric acid secretion and volume. This mechanism supports healing of ulcers and relief of symptoms associated with acid-related disorders.
CarboMer supplies Cimetidine USP with defined assay, impurity profile, and physicochemical characteristics suitable for regulated pharmaceutical manufacturing and formulation development.
The material meets USP monograph specifications and is appropriate for controlled pharmaceutical production environments.
The material is packaged in sealed, moisture-resistant, tamper-evident containers to preserve stability and handling quality. Available in laboratory, pilot, and commercial-scale quantities. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and full traceability.
Each batch is tested for identity, assay, impurity profile, water content, and related substances where applicable. Technical support is available to assist with formulation development, stability considerations, and regulatory alignment.
As with all CarboMer supplied active pharmaceutical ingredients, Cimetidine USP is supported by dependable global supply, rigorous quality systems, and expert technical guidance to ensure consistent and reliable performance across pharmaceutical applications.