Description

Cetirizine Hydrochloride EP

Cetirizine Hydrochloride EP is a high-purity second-generation antihistamine used in pharmaceutical formulations for the treatment of allergic conditions. Compliant with European Pharmacopoeia (EP) standards, it is widely utilized in oral dosage forms for the management of allergic rhinitis and chronic urticaria, offering effective symptom relief with minimal sedative effects.
Cetirizine Hydrochloride is chemically designated as (±)-[2-[4-[(4-Chlorophenyl)Phenylmethyl]-1-Piperazinyl]Ethoxy]Acetic Acid Dihydrochloride. It appears as a white to off-white crystalline powder that is freely soluble in water and suitable for formulation into tablets, syrups, and oral solutions.
In pharmaceutical and research applications, Cetirizine Hydrochloride EP is used in:
• Oral tablet and liquid formulations for allergy relief
• Treatment of seasonal and perennial allergic rhinitis
• Management of chronic idiopathic urticaria
• Pediatric and adult antihistamine products
• Research involving histamine receptor activity
• Development of non-sedating antihistamine therapies
Cetirizine Hydrochloride EP functions as a selective peripheral H1-receptor antagonist, inhibiting histamine-mediated responses such as itching, swelling, and vasodilation. Its limited penetration of the blood–brain barrier contributes to reduced sedation compared to first-generation antihistamines.
CarboMer supplies Cetirizine Hydrochloride EP with defined assay, impurity profile, and physicochemical characteristics suitable for regulated pharmaceutical manufacturing and formulation development.
The material meets EP monograph specifications and is appropriate for controlled pharmaceutical production environments.
The material is packaged in sealed, moisture-resistant, tamper-evident containers and protected from excessive light to preserve stability and handling quality. Available in laboratory, pilot, and commercial-scale quantities. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and full traceability.
Each batch is tested for identity, assay, impurity profile, water content, and related substances where applicable. Technical support is available to assist with formulation development, stability considerations, and regulatory alignment.
As with all CarboMer supplied active pharmaceutical ingredients, Cetirizine Hydrochloride EP is supported by dependable global supply, rigorous quality systems, and expert technical guidance to ensure consistent and reliable performance across pharmaceutical applications.