Description

Carboxymethyl Hydroxyethyl Cellulose

Carboxymethyl Hydroxyethyl Cellulose (CMHEC) is a high-purity, pharmaceutical-grade cellulose derivative used as a thickener, binder, stabilizer, and controlled-release matrix former in oral and topical formulations. Combining the hydrophilic properties of Carboxymethyl Cellulose with the enhanced viscosity and solution stability of Hydroxyethyl substitution, CMHEC delivers versatile functionality across dosage forms. Carboxymethyl Hydroxyethyl Cellulose

• Is a pharmaceutical-grade cellulose ether with dual substitution
• Provides efficient thickening, suspending, and binding properties
• Is suitable for oral tablets, gels, creams, suspensions, and controlled-release matrices
• Is compatible with direct compression, wet granulation, and topical formulation processes
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and supporting technical data

CMHEC is produced by etherification of purified Cellulose, incorporating Carboxymethyl and Hydroxyethyl groups that provide water solubility,  pH tolerance and controlled gelation properties. The combination enables formulators to achieve improved viscosity control and enhanced stability under processing conditions.

In pharmaceutical applications, Carboxymethyl Hydroxyethyl Cellulose is used in:

• Oral suspensions and syrups as a thickening and stabilizing agent
• Topical creams, gels, and lotions for consistent rheology and smooth texture
• Controlled-release tablet matrices to modulate drug dissolution profiles
• Bioadhesive systems improving mucosal retention
• Granulation binders for direct compression or wet granulation processes

This excipient is especially valued in formulations requiring high clarity, shear stability, and salt tolerance, making it ideal for suspensions and gels.

CarboMer supplies Carboxymethyl Hydroxyethyl Cellulose with tight control over substitution degree, viscosity, microbial content, and residual solvents to ensure batch-to-batch consistency and regulatory compliance.

The material is packaged in sealed, moisture-protected, tamper-evident containers. Available in a range of viscosities to meet specific formulation requirements. Minimum order quantities (MOQ), lead times, and full technical documentation are provided upon request.

Each batch is tested for identity, viscosity, pH, loss on drying, substitution degree, and microbial limits in accordance with internal specifications aligned to pharmacopeial standards. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and traceability documentation accompany each shipment.

As with all CarboMer cellulose derivatives, Carboxymethyl Hydroxyethyl Cellulose is supported by formulation expertise, regulatory guidance, and dependable supply to help you develop high-quality, patient-centric pharmaceutical products.