Description

Carboxymethyl β-Cyclodextrin

Carboxymethyl β-Cyclodextrin is a high-purity chemically modified cyclodextrin derivative used in pharmaceutical, biomedical, and research applications for enhanced solubility, ionic interaction, and inclusion complexation. The introduction of Carboxymethyl groups provides anionic functionality and significantly improves aqueous solubility compared to native β-Cyclodextrin.
Carboxymethyl β-Cyclodextrin appears as a white to off-white amorphous powder that is freely soluble in water, forming clear to slightly opalescent solutions. The hydrophobic internal cavity of β-Cyclodextrin remains available for host–guest complex formation, while the Carboxymethyl substitution enhances compatibility with aqueous systems and charged molecules.
In pharmaceutical and research applications, Carboxymethyl β-Cyclodextrin is used in:
• Solubility enhancement of poorly water-soluble active ingredients
• Ionic complexation with cationic and basic compounds
• Drug delivery systems including oral, topical, and parenteral formulations
• Stabilization of labile compounds against degradation
• Controlled-release and targeted delivery research
• Studies involving host–guest chemistry and cyclodextrin-based systems
Carboxymethyl β-Cyclodextrin functions by forming inclusion complexes with hydrophobic molecules while presenting a hydrophilic, negatively charged exterior. This dual functionality supports improved dissolution, stability, and formulation performance without chemical modification of the active ingredient.
CarboMer supplies Carboxymethyl β-Cyclodextrin with defined degree of substitution, consistent molecular characteristics, and high purity suitable for regulated pharmaceutical research and advanced formulation development.
The material is packaged in sealed, moisture-resistant, tamper-evident containers to preserve stability and handling quality. Available in laboratory and pilot-scale quantities. Documentation includes Certificate of Analysis (CoA), Safety Data Sheet (SDS), and full traceability.
Each batch is tested for identity, degree of substitution, solubility, moisture content, and purity profile where applicable. Technical support is available to assist with complexation studies, formulation optimization, and application development.
As with all CarboMer supplied cyclodextrin derivatives, Carboxymethyl β-Cyclodextrin is supported by dependable global supply, rigorous quality systems, and expert technical guidance to ensure consistent and reliable performance across pharmaceutical and research applications.