Description

Bisacodyl USP

Bisacodyl USP is a high-purity stimulant laxative used in pharmaceutical formulations for the short-term relief of constipation and for bowel cleansing prior to diagnostic or surgical procedures. Compliant with United States Pharmacopeia (USP) standards, it acts locally on the colon to stimulate peristalsis and promote bowel evacuation without systemic absorption. Bisacodyl USP
• Is a USP-compliant stimulant laxative for oral and rectal pharmaceutical formulations
• Promotes intestinal motility through direct action on the colon
• Is used in tablets, suppositories, and enteric-coated dosage forms
• Provides predictable bowel movement within 6–12 hours of administration
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Bisacodyl is chemically designated as 4,4′-(2-Pyridylmethylene)diphenol diacetate. It appears as a white or almost white crystalline powder, practically insoluble in water but soluble in acetone and alcohol. Its chemical stability and low hygroscopicity make it ideal for solid dosage formulations requiring controlled release.
In pharmaceutical applications, Bisacodyl USP is used in:
• Oral tablets and enteric-coated formulations for constipation relief
• Rectal suppositories for rapid bowel evacuation before medical procedures
• Combination laxative preparations with stool softeners or osmotic agents
• Research and development of gastrointestinal motility agents
• Compounded formulations requiring localized stimulant activity
Bisacodyl USP acts on the enteric nerves of the large intestine, enhancing peristaltic contractions and increasing water and electrolyte secretion into the bowel lumen. This mechanism leads to effective bowel evacuation with minimal systemic side effects.
CarboMer supplies Bisacodyl USP with control over assay, purity, residual solvents, and microbial limits. The material meets USP monograph specifications and is suitable for regulated pharmaceutical manufacturing.
The material meets packaged in sealed, moisture-resistant, tamper-evident containers. Available in laboratory, pilot, and commercial-scale quantities. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are provided upon request.
Each batch is tested for identity (IR, HPLC), assay (anhydrous basis), residual solvents, melting point, and microbial purity. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer gastrointestinal APIs, Bisacodyl USP is supported by formulation expertise, regulatory compliance, and dependable global supply to ensure safe, effective, and consistent pharmaceutical product performance.