Description

β-Cyclodextrin USP

β-Cyclodextrin USP is a high-purity cyclic oligosaccharide excipient used in pharmaceutical formulations to enhance solubility, stability, and bioavailability of active ingredients. Compliant with United States Pharmacopeia (USP) standards, it is widely used in oral, topical, and research formulations requiring molecular inclusion complexation.
β-Cyclodextrin is composed of seven α-1,4-linked D-Glucopyranose units forming a truncated cone-shaped structure with a hydrophobic internal cavity and hydrophilic exterior. This structure enables the formation of host–guest inclusion complexes with hydrophobic molecules while maintaining compatibility with aqueous systems.
β-Cyclodextrin USP appears as a white crystalline powder that is slightly soluble in water and dispersible in many formulation systems. Its ability to encapsulate hydrophobic molecules supports improved dissolution behavior and stabilization of sensitive compounds.
In pharmaceutical and research applications, β-Cyclodextrin USP is used in:
• Solubility enhancement of poorly water-soluble active ingredients
• Stabilization of oxidation- or light-sensitive compounds
• Taste masking in oral dosage forms
• Controlled-release and modified-release systems
• Inclusion complex formation for drug delivery research
• Analytical and formulation development studies
β-Cyclodextrin USP functions by forming reversible inclusion complexes with hydrophobic regions of guest molecules. This interaction can improve aqueous dispersion, protect active compounds from degradation, and influence release characteristics in pharmaceutical formulations.
CarboMer supplies β-Cyclodextrin USP with controlled purity, particle characteristics, and consistent physicochemical properties suitable for regulated pharmaceutical manufacturing and advanced formulation development.
The material meets USP monograph specifications and is appropriate for controlled pharmaceutical production environments.
The material is packaged in sealed, moisture-resistant, tamper-evident containers to preserve stability and handling quality. Available in laboratory, pilot, and commercial-scale quantities. Documentation includes Certificate Of Analysis (CoA), Safety Data Sheet (SDS), and full traceability.
Each batch is tested for identity, assay, moisture content, purity profile, and microbial limits where applicable. Technical support is available to assist with complexation studies, formulation optimization, and solubility enhancement strategies.
As with all CarboMer supplied excipient materials, β-Cyclodextrin USP is supported by dependable global supply, rigorous quality systems, and expert technical guidance to ensure consistent and reliable performance across pharmaceutical and research applications.