Description

Azelaic Acid

Azelaic acid is a high-purity, naturally occurring dicarboxylic acid used in pharmaceutical and dermatological formulations for its antimicrobial, comedolytic, and keratolytic properties. It is widely employed in topical therapies for acne vulgaris, rosacea, and hyperpigmentation due to its ability to normalize keratinization and inhibit microbial growth on the skin. Azelaic Acid
• Is a pharmaceutical-grade dicarboxylic acid for topical and dermatological applications
• Exhibits antimicrobial, anti-inflammatory, and comedolytic properties
• Is used in creams, gels, foams, and lotions for acne and rosacea treatment
• Is suitable for regulated dermatological and cosmetic formulations
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Azelaic acid is chemically designated as Nonanedioic acid (C9H16O4). It appears as a white to off-white crystalline powder, practically insoluble in water but soluble in alcohols and polar organic solvents, allowing easy incorporation into topical formulations.
In pharmaceutical and cosmetic applications, Azelaic acid is used in:
• Topical creams, gels, and foams for acne and rosacea management
• Skin-lightening and pigmentation-control formulations
• Anti-inflammatory and antimicrobial topical products
• Dermatological preparations targeting excessive keratinization
• Research and development of novel skin barrier and microbiome formulations
Azelaic acid acts through multiple mechanisms, including inhibition of 5α-reductase, suppression of keratinocyte proliferation, and reduction of Propionibacterium acnes and Staphylococcus epidermidis growth. It also exhibits antioxidant activity and promotes even skin tone without significant irritation.
CarboMer supplies Azelaic acid that is characterized by assay, purity, particle size, and microbial content. The material meets pharmaceutical-grade specifications and is suitable for regulated topical and cosmetic manufacturing.
The material is packaged in sealed, moisture-protective, tamper-evident containers. It is available in laboratory, pilot, and commercial-scale quantities. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are provided upon request.
Each batch is tested for identity (IR, HPLC), assay (anhydrous basis), melting point, water content, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer dermatological and cosmetic actives, Azelaic acid is supported by formulation expertise, regulatory guidance, and a dependable global supply chain to ensure safe, effective, and compliant product performance.