Description

Ampicillin Trihydrate USP

Ampicillin Trihydrate USP is a high-purity, broad-spectrum β-lactam antibiotic used in pharmaceutical formulations for the treatment of bacterial infections caused by both gram-positive and gram-negative organisms. Compliant with United States Pharmacopeia (USP) standards, it acts by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Ampicillin Trihydrate USP
• Is a USP-compliant β-lactam antibiotic for pharmaceutical use
• Is effective against a wide range of gram-positive and gram-negative bacteria
• Is used in oral and parenteral dosage forms including capsules, suspensions, and injectables
• Provides reliable antibacterial efficacy and broad clinical utility
• Is manufactured under Good Manufacturing Practice (GMP) certified conditions
• Is supplied with complete regulatory documentation including Certificate of Analysis (CoA) and technical data
Ampicillin Trihydrate is chemically designated as (2S,5R,6R)-6-[(2R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate. It appears as a white to off-white crystalline powder, slightly soluble in water, and stable under recommended storage conditions.
In pharmaceutical applications, Ampicillin Trihydrate USP is used in:
• Oral capsules and suspensions for systemic infections
• Injectable formulations for severe bacterial infections
• Veterinary and clinical formulations for broad-spectrum antibacterial activity
• Combination therapies with β-lactamase inhibitors to extend antimicrobial coverage
• Research and pharmaceutical development involving β-lactam antibiotics
Ampicillin Trihydrate USP acts by binding to penicillin-binding proteins (PBPs), inhibiting the transpeptidation reaction in bacterial cell wall synthesis. This results in compromised cell integrity and bactericidal activity. It remains effective in treating respiratory, urinary tract, gastrointestinal, and skin infections.
CarboMer supplies Ampicillin Trihydrate USP that is characterized by assay, potency, residual solvents, water content, and microbial purity. The material meets USP monograph standards and is suitable for regulated pharmaceutical manufacturing.
The material is packaged in sealed, moisture-resistant, tamper-evident containers. It is available in laboratory, pilot, and commercial-scale volumes. Minimum order quantities (MOQ), lead times, and documentation including CoA and SDS are provided upon request.
Each batch is tested for identity (IR, HPLC), potency, loss on drying, pH, residual solvents, and microbial limits. Certificates of Analysis (CoA), Safety Data Sheets (SDS), and full traceability documentation accompany every shipment.
As with all CarboMer antibiotic APIs, Ampicillin Trihydrate USP is supported by formulation guidance, regulatory expertise, and dependable global supply to ensure safe, effective, and compliant pharmaceutical products.