Post Date: December 30, 2024
Properties of Polycaprolactone
- Polycaprolactone (PCL) is a biodegradable and biocompatible polymer with a glass transition temperature of -60 °C and a melting point between 58 and 64 °C.
- PCL has a molecular structure that allows it to be easily manipulated and blended with other materials.
- It is a semicrystalline aliphatic polyester with amorphous regions that contribute to its toughness.
- PCL’s molecular weight can be graded, affecting its physical and mechanical properties.
- It has a low melting point, making it shapeable by hand after a few minutes in hot water.
Applications of Polycaprolactone
- PCL is used in various applications, including tissue engineering, biomedical devices, and drug delivery systems.
- It is used as an additive for resins to improve processing characteristics and end-use properties, such as tissue repair and biodegradability.
- PCL is used in hot-melt glue, laminating pouches, model making, and prototyping.
- It is also used in jewelry making and can be colored with fruit colors.
- PCL is used in biomedical applications, such as wound healing and drug release.
Degradation and Biocompatibility
- PCL degradation depends on the amount of crystallinity, polymer molecular mass, and other degradation parameters, such as environment, temperature, pH, and salinity.
- PCL undergoes degradation through two common pathways: enzymatic degradation and hydrolytic degradation.
- Enzymatically PCLdegrades with significant mass loss but very little change in molecular weight, while hydrolytic degradation reduces the molecular weight of PCL while causing minor mass loss.
- PCL is biocompatible and non-toxic, making it suitable for use in the human body.
- It is also biodegradable, reducing the risk of adverse reactions and complications.
Industrial and Medical Uses
- PCL is used in industrial applications, such as packaging, sutures, and prosthetics.
- It is used in medical applications, such as tissue engineering, wound healing, and drug delivery systems.
- PCL is used in biomedical devices, such as implants and scaffolds.
- It is also used in molecular sciences, such as molecular biology and molecular medicine.
- PCL is used in international journal publications and research studies.
Conclusion
- Polycaprolactone is a versatile and biocompatible polymer with a wide range of applications.
- Its properties, such as its low melting point and biodegradability, make it suitable for use in various industries.
- PCL’s molecular structure and physical properties make it an ideal material for tissue engineering and biomedical applications.
- Its degradation and biocompatibility make it a safe and effective material for use in the human body.
- Further research and development are needed to fully explore the potential of PCL in various fields.
CARBOMER, INC.’S POLYCAPROLACTONE PRODUCTS
CarboMer, Inc.’s offers Polycaprolactones with various molecular weights ranging from 400 to 80,000 Daltons. CarboMer also offers Polycaprolactone diols and triols and the monomer ε-Caprolactone.
6,00376 Poly(caprolactone) [24980-41-4] Mw ~45,000
6,00302 Poly(caprolactone) diol [36890-68-3] Fw 2,000
Also available in Mw 900; 400, 550 , 750, 830 and 1000
6,00378 Poly(caprolactone) triol [37625-56-2] Fw 300
6,00376 Poly(caprolactone) [24980-41-4] Mw ~45,000
Also available in Mw 10,000 and 80,000
6,00302 Poly(caprolactone) diol [36890-68-3] Fw 2,000
Also available in Mw 900; 400, 550 , 750, 830, 1000
6,00378 Poly(caprolactone) triol [37625-56-2] Fw 300
1,01604 ε-Caprolactone [502-44-3]