New Study: Lipoic Acid Assists in Circadian Rhythms & Aging Process

Biochemists from the Linus Pauling Institute at Oregon State University discovered a large amount of connections between the powerful micronutrient, Lipoic Acid, and its effects on the biological functions in living organisms.

Researchers found more evidence supporting Lipoic Acid in conjunction with overall health. The results show that Lipoic Acid plays a powerful role in the ability to reset, restore and sync normal circadian rhythms in aging animals.  Circadian rhythms are what directly affects by our bodies “biological clock” or aging process. “Circadian rhythms are physical, mental and behavioral changes that follow a roughly 24-hour cycle, responding primarily to light and darkness in an organism’s environment. They are found in most living things, including animals, plants and many tiny microbes.” (NIGMS-NIH)

The most recent findings sheds further light on lipoic acids importance. According to one of the lead researchers in the study, Dove Keith of Linus Pauling Institute, circadian rhythms break down as we age and certain enzymes don’t function as efficiently. This then leads to a decline in biological functions processing as they should and ultimately a decline in overall health. When the circadian rhythm is restored or correctly synchronized, the biological functions are improved as a result. Many of the human bodies biological functions are improved; the bodies cardiac functions, stress resistance, hormone balance, the aging process, glucose metabolism and muscle performance. Thus showing the circadian rhythm being in sync is essential for overall good health.

The study was conducted by monitoring the lipid metabolism by the liver, also termed the “circadian clock” of the liver. By taking previous information known about the dysfunction of circadian rhythms and aging, scientists were able to study the effects by feeding laboratory animals liopic acid in amounts higher than what is typically taken in a normal diet. They then observed the proteins in the liver known to dysfunction with age and cause irregular circadian rhythms. They found that lipoic acid helped remediate some of the liver dysfunction common with aging, and significantly improved the function of their circadian rhythms.

lipoic acid reset of biological clock

Notes on Circadian Rhythms:

  • Almost one-third of all genes are influenced by circadian rhythms.
  • This dysfunction in the circadian rhythm results in what is known to cause “metabolic syndrome”
  • When circadian rhythms are out of balance they can play roles in cancer, heart disease, inflammation, hormonal imbalance and many others
  • Studies with Lipoic Acid are showing it’s benefits in assisting to keep the circadian rhythms normal.
  • The amount of lipoic acid that can aid liver and normal lipid function is about 600 milligrams daily for a 150-pound human. This amount is more than could normally be obtained through diet alone.


This breakthrough will lend a hand in further studies and proof of just how important the harmony and synchronization of our circadian rhythms can be for the aging process as well as how lipoic acid can assist in promoting quality of life.

Research will continue to study the appropriate amount of lipoic acid and its benefits.

If you are interested in ordering Lipoic Acid, CarboMer offers two categories of the product right here on our website:

If you have any questions regarding how to order lipoic acid online, please Contact Us by the link above.

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